Fukui University of Technology

Dynamic Clipping Synthesis of Rotaxanes via Siliconate-Forming Reaction from Bis-Catechol, Organotrimethoxysilanes, and Secondary Amines

Abstract This study presents the dynamic clipping synthesis of [2]rotaxanes composed of catechol siliconate ion–containing crown ethers and secondary ammonium ions. These interlocked structures are stabilized through ion–ion interactions and hydrogen bonding. The σ-symmetric rota...

Lysophosphatidic acid promotes cutaneous wound healing through vascular maturation and fibroblast activation in a murine model

BACKGROUND: Impaired cutaneous wound healing is a major clinical burden, particularly among older individuals and patients with diabetes. Lysophosphatidic acid (LPA) is a bioactive phospholipid with known roles in cell proliferation, migration, and vascular formation; however, it...