Fu Wai Hospital

Associations between non-insulin-based insulin resistance surrogates and pulmonary hypertension due to left heart failure: a multicenter cohort study

Abstract Background Insulin resistance (IR) has been reported to have a close relationship with the development and adverse outcomes of various cardiovascular disorders, while its association with pulmonary hypertension due to left heart failure (PH-HF) remains to be elucidated....

Event-Weighted Desaturation Burden and Cardiovascular Mortality in Sleep Apnoea: Findings from a Large Community-Based Prospective Cohort

BACKGROUND AND AIMS: Obstructive sleep apnoea's prognostic value is limited by reliance on the apnoea-hypopnoea index (AHI), which fails to capture physiological heterogeneity of respiratory events. We developed a composite metric, event-weighted desaturation burden (EWDB), integ...

A comparison of perioperative outcomes for da Vinci robotic-assisted, laparoscopic and open surgery in oncologic procedures: a systematic literature review and meta-analysis of evidence from China

The use of robot-assisted surgery (RAS) has increased markedly in China, but comparative evidence on its perioperative performance in cancer care is dispersed across specialties and study designs. This review synthesized Chinese evidence to examine the safety and effectiveness of...

Intensive vs Standard Blood Pressure Lowering in People With and Without Chronic Kidney Disease

Importance There is uncertainty about the effects of intensive blood pressure (BP) lowering on risks of cardiovascular disease and kidney failure in patients with chronic kidney disease (CKD). Objective To assess the standardized effects of intensive BP lowering on cardiovascular...

Anesthetic management for pulsed field ablation in a patient with Eisenmenger syndrome using general anesthesia with spontaneous ventilation: a case report

Abstract Background Drug-refractory atrial tachyarrhythmia is an important precipitating factor for recurrent heart failure decompensation in patients with Eisenmenger syndrome (ES). Although percutaneous pulsed field ablation (PFA) represents a potential therapeutic option for a...

Cardiometabolic medicine in China: Burden, challenges, and strategic priorities

The development of cardiometabolic medicine (CMM) reflects a shift in cardiovascular disease (CVD) management from organ-based care toward greater cross-system integration. CMM integrates cardiovascular, endocrine, renal, and public health domains to address the bidirectional int...

Association between intraoperative 20% albumin administration and perioperative RBC transfusion in total arch replacement: a single-center retrospective cohort study

Intraoperative albumin administration has been associated with increased bleeding and transfusion in on-pump cardiac surgery. However, albumin may also protect the endothelial glycocalyx and modulate inflammation during prolonged cardiopulmonary bypass (CPB) and deep hypothermic...

EXPRESS: Association between Neurovascular Network Dysfunction and Poor Sleep Quality in Patients with Cerebral Small Vessel Disease

BACKGROUND/HYPOTHESIS: Poor sleep quality is frequently reported among patients with cerebral small vessel disease (CSVD), but its neurovascular correlates remain unclear. We examined exploratory associations between multidomain neurovascular network (NVN) measures and poor sleep...

Explainable machine learning model based on cardiac CT angiography for predicting functional improvement after atrial fibrillation ablation: a multicenter study

Radiofrequency ablation is an established therapy for atrial fibrillation (AF), but outcomes are heterogeneous in patients with concomitant heart failure (HF). Therefore, we aimed to develop an explainable machine learning (ML) model based on cardiac CT angiography (CTA) for pred...

The ventilation–perfusion differential index assists target lobe selection and improves V/Q redistribution for endobronchial valve lung volume reduction: a prospective study

Identifying the optimal target lobe remains a challenge for bronchoscopic lung volume reduction (BLVR) with endobronchial valves (EBVs). The ventilation/perfusion differential index (VQDI) has been identified as a possible tool for target lobe selection in BLVR. Twenty-four indiv...

The association between acute paroxysmal sympathetic hyperactivity and hydrocephalus or shunt complications in severe acquired brain injury: a retrospective cohort study

Abstract Background Paroxysmal sympathetic hyperactivity (PSH) and hydrocephalus frequently coexist after severe acquired brain injury (sABI) but are generally regarded as independent complications. Reports of PSH resolving after correction of hydrocephalus or shunt complications...

Delayed mechanical mitral prosthetic leaflet detachment with distal embolization and conservative management: a case report

Mechanical prosthetic valve leaflet detachment is an exceedingly rare but potentially fatal complication of valve replacement surgery, typically presenting with acute severe regurgitation and hemodynamic collapse. The underlying mechanisms remain incompletely understood, and mana...

Circumferential pulmonary vein isolation (CPVI) with adjunctive linear ablation vs. CPVI alone for long-standing persistent atrial fibrillation (SINUS): study protocol for a prospective, multi-center, randomized controlled trial

Previous studies have shown that circumferential pulmonary vein isolation (CPVI) alone has a relatively lower success rate for long-standing persistent atrial fibrillation (LSPAF). This study aims to compare the efficacy and safety between CPVI combined with modified linear ablat...

Non-opioid pharmacologic interventions for the prevention of delirium after cardiac surgery in adults: systematic review and network meta analysis

Abstract Background Postoperative delirium (POD) is a more common complication of cognitive dysfunction in adults following cardiac surgery, which leads to higher mortality, poor prognosis and increased hospital resource utilization. Given the established correlation between opio...

Left ventricular end-diastolic diameter to body surface area ratio as a continuous risk marker in left ventricular non-compaction with a dilated phenotype: a multicenter cross-sectional study

Dilated cardiomyopathy (DCM) is a risk factor for poor outcomes in patients with left ventricular non-compaction (LVNC). This study aims to identify key factors associated with the DCM phenotype in LVNC and develop a risk stratification model. This multicenter cross-sectional stu...

Prophylactic intra-aortic balloon pump in gastrointestinal cancer surgery: a potential approach to mitigate perioperative ischemic risk in severe coronary artery disease

Patients with severe coronary artery disease (CAD) requiring time-sensitive gastrointestinal cancer surgery face a dual challenge: perioperative myocardial ischemia and surgical bleeding. The optimal management strategy in this setting remains undefined. This single-center retros...

Local vs systemic inflammation and outcomes after percutaneous coronary intervention

BACKGROUND AND AIMS: Inflammation influences outcomes after percutaneous coronary intervention (PCI) in coronary artery disease (CAD). This study aimed to evaluate the relative and combined prognostic value of local coronary inflammation, and systemic inflammation for adverse out...

2026 Chinese expert consensus on perioperative management for left ventricular assist device implantation in adults

Abstract Purpose This consensus was developed to address the lack of standardized perioperative management protocols for left ventricular assist device (LVAD) implantation in China and to build on recently published national consensus documents addressing preoperative and postope...

Factors associated with venous thromboembolism in ICU patients with sepsis: A retrospective analysis using the MIMIC-IV database

This study used the MIMIC-IV v3.1 database to examine factors associated with venous thromboembolism (VTE) in adult ICU patients with sepsis, excluding those with prior VTE or ICU stays under 48 h. Among 14,784 eligible patients, 1,038 (7.0%) developed VTE during their ICU stay....