Fu Jen Catholic University

Carotid energy pulsatility index provides complementary hemodynamic information to renal function in a community-based cohort

Abstract Conventional hemodynamic, including Carotid–femoral pulse wave velocity (cfPWV), characteristic impedance (Zc), and brachial pulse pressure, do not directly quantify pulsatile energy transmission through the arterial system. Carotid energy pulsatility index (PI), derived...

Value perceptions and implementation priorities for public PHR adoption in Taiwan: an importance–performance analysis with the Chuchiming Index

Abstract Background Value perceptions of personal health record (PHR) components at the pre-adoption stage remain underexplored, despite their critical role in promoting the adoption of public PHRs. Importance–Performance Analysis (IPA) may have limitations in identifying priorit...

Multi-Locus Molecular Findings in Pediatric-Onset Inherited Metabolic Disorders: An Eight-Year Series of Outsourced Genomic Testing in Taiwan

Background/Objectives: Outsourced genomic testing can identify additional findings in patients with inherited metabolic disorders (IEMs), including lysosomal storage diseases. We examined these findings in a selected Taiwanese series. Methods: We retrospectively reviewed 13 patie...

Short-film–based world café for faculty development in medical humanities: a mixed-method evaluation across three teaching hospitals

Clinical educators play a central role in guiding the professional identity formation, ethical reasoning, and communication skills of medical students. Rapid changes in healthcare, including evolving legal frameworks, increasing visibility of gender diversity, and the emphasis on...

Buddhist Healing: Methods and Mechanisms—A Madhyamaka-Oriented Investigation

In Buddhist discourse, the path of healing often begins with awareness. Its crucial element, however, lies not in awareness alone, but in the direction toward which awareness is oriented and in the transformative process that follows from it. Ultimately, this process concerns how...

Delivery of cardiac rehabilitation through hybrid models and alternative settings by country income classification and decade: Comparisons from the International Council of Cardiovascular Prevention and Rehabilitation’s 2025 Global Audit Update

Objective Cardiac rehabilitation (CR) is an outpatient model of secondary prevention that improves patient outcomes, yet use remains limited. Hybrid/alternative CR addresses these challenges, but global availability, structure, and volumes have not been characterized since the pa...

Clinical Implications of the Novel Genetic Polymorphism Associated With Retinal Vein Occlusion: The East Asian GWAS Survey in a Single-Center Taiwanese Cohort

Purpose: To explore the single-nucleotide polymorphic features in an East Asian cohort of retinal venous occlusion (RVO) patients, to map pathogenic genes, and to analyze potential pathophysiological associations. Methods: This was a cross-sectional monocentric cohort study invol...

Effects of Freeze-Dried Burdock Root and Ultrasonic Treatment on the Growth and β-Glucosidase Activity of Lactiplantibacillus plantarum FEL112 in the Fermentation of Black Soymilk

Burdock (Arctium lappa L.) root, rich in inulin and polyphenols, has physiological activities and can serve as a nutritional source for microorganisms. The aim of this study was to investigate the effects of freeze-dried burdock root powder (BP) and ultrasonic treatment (US) on t...

CSFINet-Based Multimodal MRI Image Segmentation and Survival Prediction

Background: Brain tumors are highly lethal malignant neoplasms, for which accurate tumor segmentation and survival-day prediction are critical to treatment planning and prognostic assessment. This study establishes an exploratory two-stage analytical framework spanning multimodal...

Smartphone-related early recurrent open globe injury: A case report and literature review

Abstract: Open globe injury (OGI) is a vision-threatening ophthalmic emergency, but recurrent OGI in the same eye is exceedingly rare. This case report describes a 45-year-old male who sustained a left eye OGI from a rebounding marble block at a construction site, with visual acu...

Plural wisdoms in disaster: Responses from traditional thought and educational implications in Taiwan

This text explores how Taiwan, in the face of frequent natural disasters integrates traditional thought to build disaster resilience. Taiwanese people do not respond to disasters in a disjointed way, but instead flexibly apply the triple wisdoms of Buddhism, Confucianism, and Dao...

Multifocal mucocutaneous herpes simplex virus type 1 infection temporally associated with seasonal influenza vaccination in a young adult without a known immunocompromising condition: A case report

Seasonal influenza vaccination is widely implemented and generally safe; however, rare immunological adverse events have been reported. We describe a case of multifocal mucocutaneous Herpes simplex virus type 1 (HSV-1) infection temporally associated with seasonal influenza vacci...

Mitochondrial Quality Control in Inherited Mitochondrial Cardiomyopathy: Convergent Pathobiology and a Testable Therapeutic Framework

Inherited mitochondrial cardiomyopathies arise from pathogenic variants affecting oxidative phosphorylation, mitochondrial DNA maintenance, cardiolipin remodeling, protein import, cofactor metabolism, and mitochondrial dynamics or proteostasis. These disorders may be cardiac-pred...

LDLR variants and higher LDL-C levels are associated with premature coronary disease requiring revascularization in patients with familial hypercholesterolemia-a TCVGH-TPMI cohort analysis

The specific impacts of LDLR and APOB variants on premature coronary artery disease (CAD) that requires revascularization are less explored in Han Chinese with familial hypercholesterolemia (FH). We investigated these genetic drivers within the Taichung Veterans General Hospital-...

Association Between Unenhanced CT Features and Perioperative Outcomes in Bronchogenic Cyst Resection

Background: Reliable predictors of perioperative risk beyond symptomatology in bronchogenic cyst (BC) resection are lacking. We aimed to compare perioperative outcomes across different imaging features to identify perioperative risk factors. Methods: We conducted a retrospective...

Reproducibility-driven clinical translation of spatial multi-omics in precision medicine

Spatial multi-omics has emerged as a transformative approach for decoding tissue architecture by simultaneously profiling transcriptomic, proteomic, and epigenomic layers within their histological context. Yet despite rapid technological diversification, the transition from explo...

Comparative outcomes of Bernese periacetabular osteotomy in adolescents, young adults, and middle-aged adults

Aims: Bernese periacetabular osteotomy (PAO) is a well-established procedure for symptomatic hip dysplasia in adolescents and young adults. Its application in middle-aged patients remains debated due to concerns regarding complications and uncertain outcomes. This study evaluated...

Bacterial Superantigen-Mediated Toxic Shock: Hyperinflammatory Trajectories and Extracorporeal Immunomodulation in Streptococcal Toxic Shock Syndrome

Streptococcal toxic shock syndrome (STSS) is a fulminant manifestation of invasive group A Streptococcus infection characterized by superantigen-driven hyperinflammation, refractory shock, and rapidly progressive multiorgan dysfunction. Despite antimicrobial therapy, source contr...

Impact of Baseline Synchronous Adenoma Burden on the Risk of Metachronous Advanced Neoplasia

Background and study aim: Individuals classified as “high-risk” at initial colonoscopy face an elevated risk of metachronous advanced colorectal neoplasms (meta-ACRN), but risk heterogeneity within this group remains unclear. We aimed to stratify meta-ACRN risk among high-risk in...

How goal orientation shapes service quality: evidence from service and goods contexts

Purpose This study aims to examine how frontline employees’ goal orientations shape customer-perceived service quality and how these effects vary across service and goods contexts. It focuses on performance-prove, performance-avoid and learning goal orientations and their effects...