Fraunhofer Institute for Telecommunications, Heinrich Hertz Institute

Effectiveness of early initiation of idursulfase in infants and very young children with mucopolysaccharidosis II: a retrospective chart review in siblings

Introduction Enzyme replacement therapy (ERT) with intravenous idursulfase is the standard of care for patients with mucopolysaccharidosis II (MPS II; Hunter syndrome). Data are limited for children aged ≤12 months. This retrospective study evaluated outcomes with early ERT. Meth...

Benchmarking informal mobility in Africa: Evidence from Kigali for inclusive transportation planning

Urban mobility in sub-Saharan African cities is shaped by the widespread presence of informal transport services, yet their operational performance and spatial role remain insufficiently quantified. This study analyzes approximately 5 million motorbike taxi trips and 80,000 ride-...