Frankfurt Cancer Institute

Mechanistic insights into phage dynamics to overcome intracellular bacterial reservoirs in urinary tract infections

Abstract Recurrent urinary tract infections frequently arise from uropathogenic bacteria invading bladder epithelial cells, where they establish persistent intracellular reservoirs. Phages represent a promising therapeutic alternative to antibiotics owing to their host specificit...

Accelerating Translation of NK Cell Therapies to the Clinic: A European Perspective

Adoptive immunotherapies have emerged as a promising strategy in the treatment of hematological malignancies. To date, seven chimeric antigen receptor (CAR)-T cell products have obtained market authorization in Europe for B-cell malignancies, where they have revolutionized treatm...