Fourth People's Hospital of Shenzhen

Fc N-glycosylation heterogeneity of anti-MDA5 IgG is associated with interstitial lung disease severity via regulating FcγR/C1q signaling in MDA5 + dermatomyositis: a cross‑sectional study

<title>Abstract</title> Background To characterize Fc N-glycosylation patterns of disease-specific IgG (DSIgG) in anti-MDA5-positive dermatomyositis (MDA5 + DM) and evaluate their associations with interstitial lung disease (ILD) severity. Methods Eighty-four patients with MDA5 +...