Institution
Fourth Affiliated Hospital of Guangxi Medical University
Recent research
- Health & MedicineOpen access
CAR-based therapies in systemic autoimmunity: from deep immune depletion toward durable immune reset
Systemic autoimmune diseases are sustained by self-renewing networks of autoreactive B cells, antibody-secreting cells, pathogenic T-cell programs and tissue-resident inflammatory niches. Conventional immunosuppression and biologic therapy can reduce disease activity, but often f...
- Health & MedicineOpen access
Efferocytosis is a biological process in which phagocytic cells engulf and degrade senescent, damaged, or dead cells to prevent secondary necrosis and inflammation. This process is implicated in various diseases, including atherosclerosis (AS). Enhancing efferocytosis efficiency...
- Health & MedicineOpen access
The abscopal effect and systemic immune reprogramming: from phenomenon to therapeutic design
The classical abscopal effect is defined here as objective regression of a verified non-irradiated tumor lesion following local radiotherapy. An immune abscopal phenomenon denotes a prespecified, reproducible immune change within such a lesion that is attributable to the local in...
- Biology
CONTEXT: Inhibiting phosphodiesterase (PDE) activity to increase cyclic adenosine monophosphate (cAMP) concentrations is a core strategy in artificial sperm activation. PDE3, a key member of the PDE family, comprises two subtypes, PDE3A and PDE3B. However, their specific expressi...
- Health & MedicineOpen access
Abstract Anterior cruciate ligament rupture, a common sports‐related knee injury, often causes instability and functional impairment and increases the long‐term risk of osteoarthritis. Traditional remnant‐preserving anatomical reconstruction is the first‐line treatment for midsub...