Food and Drug Administration

A proposed evaluation of new approach methodologies for dermal toxicity assessment of botanicals

Background Botanicals are widely used in topical formulations for cosmetics, hair care, and personal care products, reflecting consumer interest in plant-derived materials. Their complex and variable composition, presents challenges for traditional toxicological approaches develo...

The INTREPID program: Linking illicit fentanyl‐containing tablets and powders seized at US borders to a common origin by combining physical/chemical identifiers and machine learning

Abstract Three US government agencies, the Drug Enforcement Administration (DEA), Customs and Border Protection (CBP), and Food and Drug Administration (FDA), established a collaborative program to leverage each agency's expertise and capabilities to characterize illicit fentanyl...

Examining the Validity of Message Evaluation Measures in the Context of Youth E-Cigarette Prevention

Despite the routine use of a variety of message evaluation (ME) measures (e.g., perceived message effectiveness) in formative research for tobacco education campaigns, studies assessing the validity of these measures for predicting actual message effectiveness (AME) (e.g., intent...