Food and Drug Administration

Occurrence of Norovirus and Hepatitis A Virus RNA in Agricultural Soil from Produce Farms in Ohio and Georgia

Although foodborne viruses are considered ubiquitous in the environment, studies on their presence in soil are largely lacking. In this field study, 168 agricultural soil samples were collected from farms in Georgia and Ohio over seven and eight months, respectively. A total RNA...

Strengthening systems to monitor antibiotics. An action oriented approach

Background Antibiotics have become lynchpins of our modern systems of healthcare, animal health and agriculture. Monitoring the types and volumes of antibiotics distributed, used and discharged across these systems is critical to provide evidence for action. With limited resource...

Injecting Pills in the Late Fentanyl Era: A Qualitative Investigation of the Procedures Used to Prepare and Inject Prescription Opioids

Background The current study offers updated information on how PWID prepare and inject prescription and illicit drugs. The main objective was to identify potential pathways and reservoirs of infection associated with the tools and techniques used to inject prescription opioids.Me...

Efficacies of three anti-Salmonella additives - bacteriophage, formaldehyde, and formic acid - within the animal food microbiota

Abstract Bacteriophage, formaldehyde, and formic acid are anti- Salmonella additives used in animal food but their effects on its microbiota are largely unknown. We applied 16S rRNA gene amplicon sequencing and shotgun metagenomics to measure animal food microbiota shifts followi...

Correlation of Nutritional Status and Blood Pressure of Apparently Healthy Primary School Pupils Aged 6–12 years in Zaria Local Government Area of Kaduna State

Anthropometric indices have become practical tools for evaluating the nutritional status of populations. Understanding the nutritional status of children has far-reaching implications for promoting the health of future generations. The necessity for routine blood pressure screeni...

A Multistate Investigation of Serious Adverse Events, including Deaths, following Ceftriaxone Injections, September 2024–August 2025

BACKGROUND: Reports of ceftriaxone serious adverse events (SAEs), including deaths, from multiple jurisdictions during December 2024-January 2025 prompted a nationwide investigation to evaluate product safety, characterize SAEs, and assess for changes in baseline adverse event oc...

Enhancing disease surveillance in Nigeria through machine learning: opportunities, challenges and strategic recommendations

Abstract Disease surveillance is fundamental to public health, enabling timely outbreak detection, efficient resource allocation, and evidence-based policymaking. In Nigeria, the Integrated Disease Surveillance and Response (IDSR) framework, while structured, is hampered by incon...

A proposed evaluation of new approach methodologies for dermal toxicity assessment of botanicals

Background Botanicals are widely used in topical formulations for cosmetics, hair care, and personal care products, reflecting consumer interest in plant-derived materials. Their complex and variable composition, presents challenges for traditional toxicological approaches develo...

The INTREPID program: Linking illicit fentanyl‐containing tablets and powders seized at US borders to a common origin by combining physical/chemical identifiers and machine learning

Abstract Three US government agencies, the Drug Enforcement Administration (DEA), Customs and Border Protection (CBP), and Food and Drug Administration (FDA), established a collaborative program to leverage each agency's expertise and capabilities to characterize illicit fentanyl...

Examining the Validity of Message Evaluation Measures in the Context of Youth E-Cigarette Prevention

Despite the routine use of a variety of message evaluation (ME) measures (e.g., perceived message effectiveness) in formative research for tobacco education campaigns, studies assessing the validity of these measures for predicting actual message effectiveness (AME) (e.g., intent...