Fleury S.A. (Brazil)

Healthcare occupancy data as an early warning indicator of infectious disease surges in São Paulo

Early detection of infectious disease surges is critical for effective public health response, yet traditional surveillance systems often suffer from delayed reporting. Here, we investigate whether passively collected occupancy data from healthcare facilities can act as an early...

Molecular investigation of coronavirus and Leptospira spp. in bats (Chiroptera, Mammalia) from Brazil

Abstract The emergence of zoonotic diseases highlights the need for continuous surveillance of wildlife, particularly bats, known as natural reservoirs of several pathogens. This study aimed to investigate the presence of coronaviruses (CoV) and Leptospira spp. in non-hematophago...

Evolutionary Dynamics-Aware De Novo Design of a Thermostable NS1-Derived Diagnostic Protein for Yellow Fever Virus

Abstract Serological diagnosis of neglected arboviruses remains hindered by extensive intra-genus cross-reactivity, compromising both assay specificity and epidemiological accuracy. In this study, we focused on yellow fever virus (YFV) as a model system to design and validate a g...

The bulging pancreas: unmasking causes beyond autoimmunity—an imaging-based approach to diffuse pancreatic enlargement

Abstract Diffuse pancreatic enlargement is frequently attributed to autoimmune pancreatitis (AIP), but several benign, genetic, inflammatory, including acute interstitial edematous pancreatitis, and malignant entities can produce a similar imaging appearance. This review provides...