First Teaching Hospital of Tianjin University of Traditional Chinese Medicine

The effect of cognitive behavioral therapy for sleep and glycemic outcomes in people with diabetes

Background: Sleep disturbances are highly prevalent in individuals with diabetes and are associated with various adverse physiological, psychological, and social consequences. A growing body of research supports the effectiveness of cognitive behavioral therapy (CBT) in managing...

Huangqi Guizhi Wuwu Decoction Ameliorates Cachexia in Lung Cancer Mice Through Regulating Amino Acid Metabolism: Insights From Transcriptomics, Metabolomics and Experimental Validation

ABSTRACT The effects and mechanisms of Huangqi Guizhi Wuwu Decoction (HGWD) in cancer cachexia remain unclear. We generated an in vivo cachexia model by implanting Lewis lung carcinoma cells into mice and treated animals with HGWD. We evaluated muscle function using grip strength...

Effects of Yijing decoction on diminished ovarian reserve: associations with mitochondrial function, apoptosis, and the PGC-1α/SIRT3/HIF-1α pathway

Abstract Diminished ovarian reserve (DOR) is a common reproductive disorder that severely impairs female fertility and lacks effective treatments. Protecting granulosa cells (GCs) has emerged as a promising therapeutic strategy. Yijing decoction (YJD), a classical Chinese herbal...

YouTube, TikTok, and Bilibili as sources of medical information on lumbar spinal stenosis

Lumbar spinal stenosis (LSS) is a common degenerative condition that impairs mobility and quality of life, particularly in older adults. Video-sharing platforms are increasingly used for health information, yet the quality and reliability of LSS-related videos and cross-platform...

Effect of electroacupuncture on postoperative delirium in older patients undergoing major surgery: a prospective, multicenter, randomized sham-controlled trial

Abstract Purpose Postoperative delirium (POD) is a common complication in older patients undergoing major surgery and is associated with prolonged hospitalization, delayed recovery, and increased mortality. This study evaluated whether perioperative electroacupuncture (EA) reduce...

Mismatch between quality and engagement in myasthenia gravis–related videos: a cross-sectional study on Chinese social media platforms

As short-video platforms increasingly play a prominent role in disseminating public health information in China, evaluating the quality of their health-related content is crucial. This study aims to systematically assess the quality, reliability, and content characteristics of vi...

From screening to gatekeeping: AIGC-detection governance in Chinese university thesis assessment — with a focus on medical education

AI-writing detectors are increasingly embedded in graduation-thesis workflows in Chinese universities. Their use is not only a technical question of classification accuracy. Once detector scores influence review, defence or degree progression, they also allocate evidentiary autho...

Quality and reliability of cancer pain management information on short-video platforms in China: a cross-sectional content analysis

Short video platforms in China have evolved into primary digital health information channels. Their algorithm-driven ecosystems raise important questions about the quality and dissemination of specialized medical content, such as cancer pain management. This study aimed to assess...

How do the measurement properties of the broad-band scales for attention-deficit/hyperactivity disorder in children perform based on the COSMIN guidelines?

This study systematically evaluated the measurement properties of ADHD-relevant subscales (i.e., subscales measuring inattention and/or hyperactivity-impulsivity) embedded within broad-band behavior rating scales for children with ADHD, using the COSMIN methodology. The aim was t...

Impacts of Copper Metabolism Disorder on Multiple Systems in Menkes Disease.

Menkes disease is a rare X-linked recessive multisystem copper metabolism disorder first reported in 1962.Recent studies have shown that its incidence and mortality rates may be underestimated due to miscarriages and early deaths.The clinical manifestations of Menkes disease are...

Efficacy and Safety Assessment of Upadacitinib for SAPHO Syndrome: A Retrospective Study of 35 Patients

OBJECTIVE: This study aimed to evaluate the efficacy and safety of upadacitinib administered over a short-term period in patients with SAPHO syndrome. METHODS: In this 12-week retrospective observational study, eligible SAPHO syndrome patients diagnosed within the past year and t...

The Heart–Kidney Axis in Heart Failure and Chronic Kidney Disease: Mechanisms, Mediators, and Therapeutic Implications

The heart–kidney axis has emerged as a central framework for understanding the bidirectional interactions that drive cardiorenal syndrome and broader cardiovascular–kidney–metabolic (CKM) disease. However, existing interpretations have often emphasized hemodynamic and neurohormon...

Efficacy, safety, and pharmacokinetics of pumecitinib nasal spray for moderate-to-severe seasonal allergic rhinitis: a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial

Background Seasonal allergic rhinitis (SAR) is a pollen-triggered condition causing nasal inflammation and quality of life impairment. Pumecitinib, a topical Janus kinase (JAK) inhibitor may modulate allergic inflammation. We evaluated the efficacy, safety, and pharmacokinetics o...

Defining a minimal clinically important difference for the Vanderbilt ADHD Parent Rating Scale in children with Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a prevalent neurodevelopmental condition in children and adolescents that poses substantial challenges to health, functioning, and well-being. This study aimed to estimate the minimal clinically important difference (MCID) for th...