First People's Hospital of Yuhang District

Establishment of stratified reference intervals for serum CA125 using five algorithms based on real-world big data and evaluation of clinical performance

To address the lack of localized validation and precise stratification of reference intervals (RIs), this study used real-world health-checkup big data and five indirect algorithms to establish RIs for serum CA125, evaluated the consistency among the algorithms and their clinical...

Exploratory single-nucleus transcriptomic analysis of endothelial heterogeneity and ferroptosis-related gene patterns in a human hepatocellular carcinoma sample

Background Endothelial heterogeneity may contribute to vascular remodeling in hepatocellular carcinoma (HCC), while ferroptosis-related iron handling intersects with hypoxic, inflammatory, and metabolic stress. We therefore characterized endothelial transcriptional states in a pu...

An expert-level generalist AI for abdominal CT diagnosis

Artificial intelligence (AI) in radiology aspires to deliver expert-level diagnosis across diverse clinical tasks, yet existing supervised strategies remain limited in scope. We developed RADAR, a generalist vision-language model trained on more than 400,000 contrast-enhanced abd...

Are jet speeds governed by accretion modes?

Abstract Relativistic jets are observed in both stellar-mass black hole X-ray binaries (BHXRBs) and active galactic nuclei (AGNs), yet their bulk Lorentz factors differ systematically—those in black hole X-ray binaries are typically below ~2, whereas AGN jets can reach ~50. The o...

Deep Reinforcement Learning-Guided Design of Broadband Electromagnetic Wave Absorbing Coatings

Abstract Artificial intelligence-assisted design of electromagnetic wave absorbing coatings is often restricted to geometry or topology optimization within fixed materials. Here, we present a modular particle swarm optimization−proximal policy optimization (PSO−PPO) framework for...

Influence of Operation Mode On The Performance and Component Matching and Multi-Objective Optimization of A Multi-Stream Adaptive Cycle Engine

Abstract The multi-stream adaptive cycle engine (ACE) represents a transformative propulsion concept for next-generation aircraft, offering the capability to dynamically balance thrust, efficiency, and thermal management across widely varying mission conditions. By incorporating...

Preoperative risk factors and 180-day postoperative mortality in type a aortic dissection: a cohort study

To explore modifiable risk factors associated with 180-day postoperative mortality based on preoperative examinations in patients with type A aortic dissection. From August 2021 to November 2024,86 patients with TAAD attending the Emergency and Trauma Center of the First Affiliat...