First Affiliated Hospital of Chengdu Medical College

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

ABSTRACT The sterility and controllable biological functionalities of implantable medical devices determine their lifespan, safety, and therapeutic efficacy. Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, we have developed a...

The Association Between Metabolic Score for Insulin Resistance and the Risk of Hypertension

Abstract Objectives To systematically investigate the association and dose-response relationship between the metabolic score for insulin resistance (METS-IR) and the risk of hypertension, using data from a prospective cohort study of Chinese adults. Methods A total of 4866 adults...

Comparative Analysis of Clinical Manifestations of Gasless Endoscopic Surgery via Transaxillary and Subclavicular Approaches in Unilateral cN0 Thyroid Cancer

AIM: To compare the clinical efficacy and safety of gasless endoscopic radical thyroidectomy via the transaxillary approach versus the subclavicular approach for unilateral cN0 thyroid cancer.METHODS: A total of 415 patients with unilateral cN0 thyroid cancer admitted between Jan...

Engineered desialylated platelet membrane camouflaged liposomes for the regulation of kupffer cells and hepatic stellate cells in treatment of liver fibrosis

The intercellular crosstalk and reciprocal activation between Kupffer cells (KCs) and hepatic stellate cells (HSCs) are critical drivers of liver fibrosis progression. Nonetheless, the co-regulation of KCs and HSCs is hindered by their distinct anatomical locations and the pathol...

Association Between Psoriasis and Overactive Bladder Among US Adults: A Study Based on 2005–2006 and 2009–2014 National Health and Nutrition Examination Survey

BACKGROUND: Both psoriasis and overactive bladder (OAB) are considered systemic conditions that share many inflammatory or immune pathways in the pathogenesis. One previous study found patients with psoriatic arthritis (PsA) reported significantly higher bladder autonomic dysfunc...

Retrospective analysis of postoperative complications and risk factors in middle ear surgery

Background Postoperative complications following middle ear surgery present ongoing challenges despite advances in surgical techniques. A comprehensive analysis of complication patterns, associated risk factors, and their interactions with patient comorbidities is needed to impro...

The Multi-Layered Effect of Panaxatriol Saponins in Preventing Diabetic Nephropathy in Mice

Background: Diabetic nephropathy (DN) is a common microvascular complication of diabetes and the leading cause of end-stage renal disease (ESRD). Nearly 40% of people with diabetes will develop DN, and DN accounts for 23% of ESRD cases in China. Dysfunction of the gut-kidney axis...