Fifth Tianjin Central Hospital

Ki-67 Proliferation Index Improves the Prognostic Stratification Accuracy of International Staging System in Newly Diagnosed Multiple Myeloma

Objective: To investigate the clinical characteristics and prognostic significance of distinct Ki-67 proliferation indices in patients with newly diagnosed multiple myeloma (NDMM). Methods: A retrospective analysis of clinical data from 307 NDMM patients admitted to the Second Ho...

Ovarian microcystic stromal tumor with unusual expression of AR and partial S100: a case report and literature review

The ovarian microcystic stromal tumor (MCST) is a rare, typically benign stromal neoplasm characterized by a distinctive microcystic architecture and nuclear β-catenin immunoreactivity. This report describes a case that exhibits unusual AR positivity and partial S100 positivity....

Characteristics of meta-analyses of multi-indication drugs: a systematic review of systematic reviews

Multi-indication drugs (MIDs) are increasingly common, but their meta-analyses face methodological challenges due to heterogeneity across indications. This review aims to characterize the methodological and reporting approaches of meta-analyses evaluating MIDs. We conducted a sys...

Quality and reliability of cancer pain management information on short-video platforms in China: a cross-sectional content analysis

Short video platforms in China have evolved into primary digital health information channels. Their algorithm-driven ecosystems raise important questions about the quality and dissemination of specialized medical content, such as cancer pain management. This study aimed to assess...

Evaluating the efficacy of a novel endometrial receptivity test in improving pregnancy outcomes for Chinese in vitro fertilization patients: a single-center retrospective study

Abstract Background Current evidence on whether endometrial receptivity tests improve pregnancy outcomes among in vitro fertilization (IVF) patients remains conflicting and limited. This study aimed to evaluate the efficacy of HerRecepta, a novel transcriptomic endometrial recept...