Ferring Pharmaceuticals (Switzerland)

Hydantoin Impurity Formation During Peptide N-Terminal Acetylation with Acetic Anhydride

Abstract Previously unreported N-terminal hydantoin and N-acetyl hydantoin impurities were observed during peptide N-terminal acetylation with acetic anhydride under commonly used base/solvent conditions. The impurities were isolated and structurally characterized by HRMS and NMR...

Soil health assessment using buried cotton underpants with the help of 1000 citizen scientists

Societal Impact Statement Soil is a vital resource for life on Earth. Although many soils are degraded, societal awareness of soil‐related issues is limited. To highlight soil as a key resource and fascinating study system, we initiated a citizen science project together with 100...