Federal Research Centre of Nutrition and Biotechnology

Cytokine Profiles in Cervical Intraepithelial Neoplasia: Associations with Lesion Severity and Exploratory Treatment Response

Background: Persistent infection with high-risk human papillomavirus (hrHPV) is the principal cause of cervical intraepithelial neoplasia (CIN). Cytokines regulate antiviral immunity and tissue remodeling, and cytokine profiling may provide additional information about the biolog...

Evaluation of inert gases as alternatives to Carbon Dioxide for stunning pigs: effects on gas stability, effectiveness and animal welfare

The European Union requires pigs to be stunned before slaughter, with Carbon Dioxide (CO₂) being the most common method, although it is increasingly criticized for its aversiveness. This study evaluated inert gases for stability, effectiveness, and animal welfare. Ten gas mixture...

Linker Engineering of Hybrid Triazole-Thiazolidine Antifungals Identifies a Promising Lead Against Drug-Resistant Candida Species

Background: The emergence of antifungal resistance and the limited number of clinically available antifungal drug classes necessitate the development of new agents with improved efficacy and safety. We investigated how linker architecture influences the antifungal activity and le...