Federal Research Center of Fundamental and Translational Medicine

A Curated Phenotype-Linked HIV-1 Sequence Dataset for Machine Learning Approaches to Tropism Prediction, Disease Progression and Proviral Reservoir Studies

HIV-1 tropism toward the CCR5 and CXCR4 coreceptors is an important viral characteristic associated with cell entry, the potential use of specific entry inhibitors, studies of disease progression, and analyses of proviral reservoirs. The development of tools for genotypic tropism...