Fachhochschule Wiener Neustadt

Infection Prevention and Device Pocket Management in Cardiac Implantable Electronic Devices: Emerging Strategies

Abstract Purpose of Review Cardiac implantable electronic device (CIED) infection remains one of the most serious complications of device therapy, causing significant morbidity, mortality, healthcare utilization, and costs. Despite advances in device technology and preventive str...

Development of a prospective clinical workflow for proton beam therapy of ventricular tachycardia

Abstract Purpose This study presents a prospective preclinical workflow for proton beam therapy of refractory ventricular tachycardia (VT), covering target transfer, treatment planning (TP), and beam gating. Methods Photon-based stereotactic arrhythmia radioablation (STAR) protoc...

The Efficacy of Different Treatment Options in Cutaneous Sarcoidosis: A Meta-analysis of RCTs

Cutaneous sarcoidosis is a granulomatous skin disease associated with significant quality-of-life impairment. Evidence from randomized controlled trials (RCTs) guiding systemic or targeted therapy remains limited. To assess the efficacy and safety of pharmacological therapies for...

Safety and Effectiveness of a Novel Dual-Energy Radiofrequency/Pulsed Field Ablation Catheter: 12 Month Results of the FlexPulse Study

BACKGROUND AND AIMS: Pulsed field (PF) ablation is increasingly used to treat paroxysmal atrial fibrillation (PAF). FlexPulse (NCT06676072) was conducted to evaluate safety and effectiveness of a novel dual-energy, flexible-tip focal ablation catheter with radiofrequency and PF f...

Histological aging signatures for monitoring tissue-specific aging and disease

Aging is the primary risk factor for chronic disease and is characterized by profound structural and architectural remodeling of human tissues. Here, we present a comprehensive assessment of these changes using 25,712 whole-slide histopathological images from 40 tissue types acro...