European X-Ray Free-Electron Laser

Molecular mechanism of calcium inhibition in viral channelrhodopsins

Abstract Viral channelrhodopsins (VCR1s) are giant-virus-encoded light-gated channels permeable to monovalent and divalent cations, including Na + and Ca 2+ ions, and inhibited by millimolar Ca 2+ concentrations. Here, we combine X-ray crystallography, time-resolved UV-vis spectr...

A quantitative framework for ultrafast ptychography through digital twin control of extreme-ultraviolet beams

Ptychography is a powerful imaging method that has transformed microscopy at large-scale and laboratory facilities. Its combination with extreme-ultraviolet light has enabled tabletop microscopes that visualize nanoscale dynamics and characterize ultrafast pulses. However, the pe...