Escola Superior de Ciências da Santa Casa de Misericórdia de Vitória

Clinical and virological characterisation of Oropouche, dengue, and chikungunya during simultaneous co-circulation in the State of Espírito Santo, Brazil: a retrospective observational study

Background Dengue (DENV), chikungunya (CHIKV), and Oropouche (OROV) viruses co-circulate in Brazil and present with overlapping acute febrile syndromes, complicating clinical differentiation. Comparative data integrating clinical phenotyping and viral load dynamics across these a...

Flow cytometry as a tool for assessing reactive oxygen species-related fluorescence in peripheral blood leukocytes from children and adolescents with asthma

Background Asthma is characterized by airway inflammation and bronchial hyperreactivity, with increased production of reactive oxygen species (ROS). Assessing oxidative stress is relevant to disease pathophysiology, but many methods have limitations in pediatric populations . Obj...

Endovascular therapy versus best medical treatment in pediatric acute ischemic stroke: A systematic review and meta-analysis

Purpose This systematic review and meta-analysis evaluates endovascular therapy (EVT) versus best medical treatment (BMT) in pediatric acute ischemic stroke (AIS) due to large-vessel occlusion. Methods Systematic searches were conducted across PubMed, Cochrane, and Embase, incept...