Erasmus MC Cancer Institute

Transient (Pro)renin receptor silencing disrupts proximal tubule development in human kidney organoids

The (pro)renin receptor [(P)RR] plays a crucial role in murine kidney development, but its function in human kidneys remains poorly understood due to the lack of suitable research models. Human induced pluripotent stem cell (iPSC)-derived kidney organoids recapitulate early kidne...

Facilitating advance care planning in oncology: study protocol for the evaluation of a tailored implementation of an advance care planning tool (the INDEED study)

Abstract Background Advance care planning (ACP) improves patient outcomes, but integration of ACP in daily practice for patients with cancer in hospitals remains suboptimal. Systematic implementation of tools to facilitate ACP could overcome the barriers for ACP. In this study we...

Cost‐Effectiveness of Radiofrequency Ablation for Benign Non‐Functioning Thyroid Nodules: A Systematic Review

ABSTRACT Purpose This systematic review tests the hypothesis that radiofrequency ablation (RFA) for benign non‐functioning thyroid nodules is associated with favourable cost‐effectiveness compared with surgery. Materials and Methods A systematic literature search of multiple data...