Erasmus Hospital

Serum neurofilament light chain and the 2024 McDonald criteria for multiple sclerosis: a retrospective cohort study

Background The 2024 McDonald criteria broaden the definition of multiple sclerosis (MS), enabling diagnosis in individuals with asymptomatic MRI findings or clinical presentations not meeting the 2017 criteria. We assessed whether these criteria identify such cases using independ...

Baseline Clearance and Early Troughs Identify Candidates for Early Therapeutic Drug Monitoring During Infliximab Induction in Inflammatory Bowel Disease

ABSTRACT Background and Aims The value of therapeutic drug monitoring during infliximab induction remains uncertain. We evaluated whether baseline infliximab clearance and early exposure metrics identify candidates for potential early proactive therapeutic drug monitoring during...

The Smart MDI System in People With Type 1 Diabetes and High HBA1C: A Randomized Controlled Trial Demonstrating That Response to Alerts Drives Outcomes

ABSTRACT Aims The aim was to assess the efficacy and safety of the smart multiple daily injections (MDI) system versus MDI plus continuous glucose monitor (CGM) in people with Type 1 diabetes and HbA1c ≥ 8%. Material and Methods After a 3‐week run‐in, 143 participants were random...

Expired endoscopic devices remain sterile and functional: an international multicentre study challenging current shelf-life criteria

Background and study aims Expired medical devices represent an environmental and economic concern, yet their magnitude and true shelf life remain poorly defined. We aimed to quantify the volume and cost of expired endoscopic devices and evaluate their sterility and functionality...

Exploring seismocardiographic signals in children with congenital heart disease: a prospective pilot study

Abstract Congenital heart diseases (CHD) are the most common congenital malformations, and early identification is essential for reducing their morbidity and mortality. This prospective pilot study evaluated the feasibility and exploratory diagnostic relevance of seismocardiograp...

Low awareness of and adherence to preventive guidelines for hepatitis B reactivation among Belgian specialist physicians: the CHOICe study

Despite preventive screening guidelines and antiviral prophylaxis, hepatitis B virus (HBV) reactivation continues to be a problem in clinical practice, resulting in patient mortality. The CHOICe study has two main research objectives: firstly, to identify knowledge gaps relating...

The Transition of Youth With Diabetes From Pediatric to Adult Diabetes Care Services: A Consensus Report of the Joint Working Group of the International Society for Pediatric and Adolescent Diabetes (ISPAD), the European Association for the Study of Diabetes (EASD), and the American Diabetes Association (ADA)

Young adulthood is a period of significant and unique physiological, psychological, sexual, and social upheaval. Related challenges can have an impact on effective diabetes self-management, with high rates of unplanned health care use recorded for many, and consequent increases i...