ENT and Allergy

Changes in neurodevelopmental outcomes from 24 to 36 months among children HIV-exposed uninfected (CHEU) and HIV-unexposed (CHU)

Objective: To compare neurodevelopment through 36 months between breastfed children who are HIV-exposed and uninfected (CHEU) exposed to maternal dolutegravir (DTG)-based antiretroviral therapy (ART) and children born to mothers without HIV (CHU). Methods: We enrolled a prospecti...

T cell–intrinsic AIM2 exacerbates lung inflammation in OVA-LPS- and HDM-induced asthma models

Asthma is a heterogeneous inflammatory airway disease characterized by immune dysregulation, airway hyperresponsiveness (AHR), and excessive immune activation. Although NLRP3 (NOD-like receptor family pyrin domain-containing 3) has been extensively studied in asthma, its role rem...