Emergency Services College

Interstitial Fluid Load Support in Human Articular Cartilage: Effects of Degeneration, Loading, and Material Properties via Combined Experimental Testing and Computational Modeling

Abstract Interstitial fluid pressurization plays a key role in cartilage mechanics, as it enables load support, reduces solid matrix stress, and limits solid–solid contact, thereby minimizing wear and friction. Because direct measurement of interstitial fluid load support is chal...

Health-related quality of life and the impact of dispositional life orientation in multiple sclerosis or rare neurological diseases

Abstract Background Health-related quality of life (HRQoL) is affected in multiple sclerosis (MS). Sense of coherence (SOC) and optimism/pessimism may be associated with HRQoL. Objective To compare HRQoL in patients with MS and rare neurological diseases (RND), and to evaluate th...