Elisabeth-TweeSteden Ziekenhuis

Hemocytometric Parameters Associated with Bacterial and Viral Etiology in COPD Exacerbations: An Exploratory Analysis

Exacerbations of Chronic Obstructive Pulmonary Disease (ECOPD) are often triggered by bacterial and viral infections, yet current diagnostic methods are time-consuming and biomarkers (e.g. C-reactive protein (CRP)) show limited accuracy in differentiating between these triggers....

Plasma metabolomics reveals candidate biomarkers associated with individual treatment response in psoriatic arthritis

Psoriatic arthritis (PsA) is a clinically heterogeneous inflammatory disease for which optimal treatment selection remains unclear. Robust biomarkers that predict treatment response and identify patient-specific factors to inform treatment choice could advance precision medicine...

Achieving physiologic distensibility targets frequently requires modification of standard cruroplasty during anti-reflux surgery

Abstract Background Intraoperative EndoFLIP provides objective assessment of esophagogastric junction (EGJ) distensibility during anti-reflux surgery, and final distensibility index (DI) values of 2.0–3.5 mm 2 /mmHg have been associated with improved reflux control while minimizi...

Significant other reported outcome measures within European cohorts of severely injured patients: A systematic review

Abstract Purpose Major trauma can have a long-term impact, leading to diminished health-related quality of life (HRQoL) for patients and their significant others (SOs). Patient reported outcome measures (PROMs) make this impact visible, providing expectation- and self-management....

Endotracheal intubation practices, success rates and adverse events in four Dutch emergency departments: a multicentre retrospective study

Endotracheal intubation in the emergency department (ED) is a high-risk intervention associated with significant complications. Contemporary European data on emergency airway management remain limited, and no published data are available from the Netherlands. This study aimed to...