Eindhoven University of Technology

Growth Plate Morphogens as Potential Modulators of Cellular Tissue Remodeling by Annulus Fibrosus Cells

ABSTRACT Background Adolescent Idiopathic Scoliosis (AIS) is a spinal deformity of unknown etiology that begins in the intervertebral disc and emerges during pubertal growth. In the vertebral growth plate, adjacent to the disc, powerful growth plate morphogens (GPMs) modulate thi...

Protein LanguageModel Decoys for Target Decoy Competitionin Proteomics: Quality Assessment and Benchmarks

Abstract Large-scale proteomics relies heavily on target–decoy competition for false discovery rate estimation in peptide identification, and the performance of this strategy depends strongly on the design of the decoy database. Classical generators such as reversal and shuffling...

Signal-induced recruitment and dispatchment in reconfigurable phase-separated protocell networks

Abstract The construction of protocell networks with self-regulated spatial dynamics and functions is an important challenge in the emerging field of colloidal systems chemistry. Existing strategies predominantly produce protocell networks with fixed or randomly distributed spati...

Delivering building demand flexibility for grid-interactive operation: from perception and cognition to decision, execution, and verification

As both buildings and power systems undergo rapid decarbonization, demand flexibility (DF) in buildings has emerged as a key enabler for renewable energy integration, grid reliability, energy resilience, and efficient and low carbon operation. By dynamically adjusting building en...

Generalizing reduced rank extrapolation to low-rank matrix sequences

Abstract Reduced rank extrapolation (RRE) is an acceleration method typically used to accelerate the iterative solution of nonlinear systems of equations using a fixed-point process. In this context, the iterates are vectors generated from a fixed-point mapping function. However,...

Liquid Crystal Elastomer‐Based Haptic Pixel Arrays at Your Fingertips for Advanced Human–Machine Interfaces

The sense of touch is underutilized in our digital lives, especially when compared to the prevalence and complexity of information transfer through our visual and auditory interactions with devices; the impact of this is profound as touch plays a major role in our perception of o...

Fusion at scale: Critical enablers in global energy transitions

Fusion is a promising sustainable energy source that can potentially contribute to achieving the most ambitious climate goals with firm carbon-free baseload electricity. Due to recent advancements, fusion is transitioning from a purely research stage to a pre-commercialisation ph...

Extinction Prediction and Emission Analysis of a Bluff-Body Stabilized Ammonia-Hydrogen-Nitrogen Premixed Flame With Conjugate Heat Transfer

Abstract Ammonia/hydrogen blends represent a promising carbon-free fuel for gas turbine combustors. To minimize the NOx emission, premixed ammonia/hydrogen/nitrogen flames under ultra lean equivalence ratios are investigated. This paper simulates the extinction process of a bluff...

Morphology-based screening for sickle cell disease using low-cost automated microscopy and machine learning

Abstract Sickle cell disease (SCD) and β-thalassemia are the most common monogenic diseases, disproportionately affecting low- and middle-income countries, where low-cost and accurate diagnostic tools are needed to reduce the global disease burden. Although the sickling test is c...

Secure Set-based State Estimation for Safety-Critical Applications under Adversarial Attacks on Sensors

Set-based state estimation provides guaranteed state inclusion certificates that are crucial for the safety verification of dynamical systems. However, when system sensors are subject to cyberattacks, maintaining both safety and security guarantees becomes a fundamental challenge...

Statistical Monitoring of Multivariate Count Data From Real‐Time Particle Counters

ABSTRACT In the pharmaceutical industry, production environments are monitored for bacterial contamination. Particle counters are increasingly investigated for real‐time monitoring of viable microorganisms using count data for different particle size intervals. Monitoring these m...