Education Training And Research

Yield of Low Serum Vitamin B12 Results in General Pediatric Outpatient Practice: Age-Specific Patterns and Associations with Testing Indications and Recorded Clinical Features

Background/Objectives: Serum vitamin B12 testing is frequently ordered in pediatric outpatient practice, either routinely or incidentally as part of broad laboratory panels or in response to symptoms and nutritional concerns; however, how the yield of low serum vitamin B12 result...

Comparative Two-Year Outcomes of Three Different Three-Piece Intraocular Lenses in Flanged Intrascleral Fixation

Background and Objectives: To compare 2-year positional stability, endothelial preservation, and visual outcomes of three three-piece intraocular lenses (IOLs) implanted by the Yamane technique: Eyecryl (polypropylene haptics, 5° haptic angulation), Sensar OptiBlue AR40e (polymet...

Association of Platelet–Albumin–Bilirubin and Albumin–Bilirubin Scores with Angiographic No-Reflow in Patients with ST-Segment Elevation Myocardial Infarction Undergoing Primary PCI

Background: The platelet–albumin–bilirubin (PALBI) and albumin–bilirubin (ALBI) scores integrate routinely available laboratory parameters with potential relevance to microvascular injury. We investigated their associations with angiographic no-reflow and incremental predictive v...

Prognostic Value of Systemic Inflammation Markers and Clinical Factors in Grade 4 Diffuse Glioma: A Multicenter Retrospective Real-World Study

Background/Objectives: Systemic inflammation contributes to tumor growth and spread. We aimed to evaluate the association of pretreatment inflammatory indices and clinical and laboratory factors with survival in newly diagnosed grade 4 diffuse glioma. Methods: A total of 120 pati...

Near-complete circumferential intramural bladder gas in emphysematous cystitis: a case report

Abstract Background Emphysematous cystitis is a gas-forming infection of the urinary bladder characterized by intramural and occasionally intraluminal gas. Although diabetes mellitus is a common predisposing condition, the disease may also develop in association with urinary stas...

The Comparative Prognostic Value of the Interim PET Deauville Score and ΔSUVmax in Classical Hodgkin Lymphoma: A Real-World Study of Imaging and Inflammatory Markers

Background: Interim [18F]FDG-PET/CT with the Deauville score (DS) is central to response assessment in classical Hodgkin lymphoma (cHL). Quantitative ΔSUVmax and the lymphocyte-to-monocyte ratio (LMR) may refine the DS, but ΔSUVmax thresholds vary across cohorts and have rarely b...

Maternal and Neonatal Outcomes Among Syrian Refugee Women: A Retrospective Study from a Tertiary Hospital in Türkiye

To compare maternal, obstetric, neonatal, and hematological outcomes between Syrian refugee women and Turkish women giving birth at a tertiary hospital in Türkiye. Retrospective cross-sectional study. Sakarya Training and Research Hospital, a tertiary public hospital in Türkiye,...

Association Between Nasal Septal Deviation Types and Eustachian Tube Function: A Prospective Observational Study

OBJECTIVE: This study aimed to objectively and subjectively evaluate the effect of nasal septal deviation (NSD) types, classified according to the Baumann system, on Eustachian tube function. METHODS: A total of 107 NSD patients (78 males, 29 females; mean age: 35.39 ± 9.55 years...

Simultaneous Reconstruction of Early Orbital Implant Exposure and Lower Eyelid Symblepharon Using an Oral Mucosal Membrane Graft Following Evisceration

A 72-year-old male patient presented with early orbital implant exposure and lower eyelid symblepharon after evisceration surgery performed at an outside center after severe ocular penetrating trauma. A single-stage reconstruction was performed. After release of the lower eyelid...

Microbiological monitoring of scuba cylinders under routine filling and seasonal diving conditions

Introduction: The aim of this study was to monitor the microbiological status of the inner surfaces of scuba cylinders under routine air filling conditions and to assess whether microbiological contamination emerges or persists over time. Methods: A prospective longitudinal micro...

Biomarkers of Treatment-Escalation Risk by Obesity Status in Pediatric Asthma: A Development and External Validation Cohort Study

Background/Objectives: Obesity may alter the prognostic value of biomarkers in childhood asthma. We examined whether transforming growth factor beta 1 (TGF-β1), soluble suppression of tumorigenicity 2 (sST2), C-X-C motif chemokine ligand 8 (CXCL8), and insulin-like growth factor...

Beyond Systemic Inflammation: The Complementary Role of Cellular Stress Markers in Predicting STEMI Outcome. Comment on Magureanu et al. Early Inflammatory Biomarkers, Ventricular Dysfunction and In-Hospital Mortality in Patients with ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention. Diagnostics 2026, 16, 1978

I read with interest the recently published article by Magureanu et al [...]

Maternal bonding and psychological symptoms among women with and without COVID-19 infection: a comparative cross-sectional study

BACKGROUND: Childbirth during the COVID-19 pandemic involved infection-control measures and changes in maternity care that may have increased psychological stress and affected early mother-infant bonding, particularly among women infected at delivery. OBJECTIVE: This study aimed...

Not So Innocent After All: Cardiomyopathy Induced by ‘Benign’ Premature Atrial Contractions

ABSTRACT Premature atrial contractions (PACs) are not generally considered a cause of arrhythmia‐induced cardiomyopathy, although a high PAC burden has been reported to induce this entity in several cases. We present the case of a 36‐year‐old man who presented with severe left ve...

Validity and reliability of the Turkish version of the ORTO-R in an adolescent clinical sample

Orthorexia nervosa refers to a pathological preoccupation with healthy eating characterized by rigid dietary rules, excessive concern about food purity, and distress when these rules are violated. Despite growing clinical interest, validated instruments for assessing orthorexic t...

Is 400 Gy enough for every tumor? The 3 cm cutoff and a modified BCLC classification for predicting complete response after radiation segmentectomy in hepatocellular carcinoma

To evaluate the relative contribution of the 400 Gy perfused liver absorbed dose (PLAD) threshold and tumor size in predicting complete response (CR) after yttrium-90 (Y-90) radiation segmentectomy (RS) in hepatocellular carcinoma (HCC), and to investigate the prognostic discrimi...

ROX index and NEWS2 for 28-day mortality prediction in emergency department patients with acute dyspnea: a prospective observational study

Acute dyspnea is a frequent and high-risk presentation in emergency departments (ED), requiring rapid identification of patients at increased risk of deterioration and mortality. This study aimed to compare the accuracy of the Respiratory Rate–Oxygenation (ROX) index and National...

Outcomes of Percutaneous Interventions for Aortic Coarctation: Experience from a Tertiary Care Center

BACKGROUND: Coarctation of the aorta (CoA) is a congenital obstructive anomaly that may remain undiagnosed until adulthood, often presenting with systemic hypertension. While percutaneous interventions, including balloon angioplasty and stent implantation, are increasingly utiliz...

The Effect of Preoperative Preservative Burden on the Success of Ab-Interno Trabeculotomy

Purpose To evaluate the effect of preoperative cumulative preservative burden on 1 year surgical outcomes of Kahook Dual Blade (KDB) and Gonioscopy-Assisted Transluminal Trabeculotomy (GATT).Methods This retrospective study included 46 eyes (23 KDB, 23 GATT). A Preservative Burde...

First-trimester aggregate index of systemic inflammation and adverse pregnancy outcomes in hospitalized women with threatened miscarriage: a single-center retrospective cohort study

Abstract Background Complete blood count-derived inflammatory indices have been associated with miscarriage, but the incremental value of the aggregate index of systemic inflammation (AISI) beyond established indices such as the systemic immune-inflammation index (SII) remains un...