Education Department of Hunan Province

Potential of plasma metagenomic next-generation sequencing to guide antibiotic therapy in acute necrotizing pancreatitis with early fever: a prospective multicenter cohort study

Indiscriminate antibiotic use remains common in febrile patients with acute necrotizing pancreatitis (ANP), particularly during the early phase. Metagenomic next‑generation sequencing (mNGS) has shown diagnostic utility for infected pancreatic necrosis (IPN) and may offer a means...

A Pan‐Cancer Single‐Cell Atlas of Bone Metastases Reveals Convergent Malignant Programs and Coordinated Immune Dysfunction

ABSTRACT Bone metastases (BoMs) are a major clinical challenge across cancer types, yet mechanistic insights remain limited by small cohorts and insufficient profiling depth. Here, we present a single‐cell RNA sequencing atlas of 95 BoMs, 22 healthy bone marrows (hBMs) and 129 pr...

Phase Transition Mediated Solvation Structure Regulation in Quasi‐Solid‐State Composite Electrolyte for High‐Voltage Sodium Batteries

ABSTRACT Quasi‐solid‐state composite electrolytes (QSSEs) represent a promising approach to fabricating high‐energy rechargeable batteries, but their practical implementation is hindered by structural instability and interfacial incompatibility. In this study, a QSSE was prepared...

A robust adaptive InSAR-GNSS fusion approach for three-dimensional surface deformation monitoring

Urban land subsidence threatens coastal infrastructure, especially in reclaimed and densely developed areas. Single-geometry InSAR (Interferometric Synthetic Aperture Radar) provides wide-area LOS (line-of-sight) deformation but is limited in resolving 3D (three-dimensional) grou...