École Centrale de Lyon

A deterministic particle approximation for a fourth-order equation

We provide a deterministic particle approximation to a fourth order equation with applications in cell-cell adhesion. In order to do that, first we show that the equation can be asymptotically obtained as a limit from a class of well-posed nonlocal partial differential equations....

Multiband High- Q Terahertz Resonances in a Twisted Triangular Moire Metasurface

Abstract Bound states in the continuum (BICs) are nonradiative modes embedded within the continuous spectrum of propagating states that remain perfectly localized without leaking into radiation channels. Symmetry-protected BICs (SP-BICs) are induced by structural symmetry at the...

Screening colorectal tumor-associated fibroblasts using dual-channel THz biosensor

In clinical oncology, label-free identification of colorectal tumor-associated fibroblast (CAF) subtypes is challenging. In this work, a terahertz (THz) metasurface exhibiting dual channels of probation, quasi-bound states in the continuum (q-BICs) and electromagnetically induced...

Gradient-based active learning with Gaussian processes for global sensitivity analysis.

Global sensitivity analysis of complex numerical simulators is often limited by the small number of model evaluations that can be afforded. In such settings, surrogate models built from a limited set of simulations can substantially reduce the computational burden, provided that...

Deep molecular profiling of lung neuroendocrine tumours and supra-carcinoids

BACKGROUND: Lung neuroendocrine tumours (NETs, also known as carcinoids) are rapidly rising in incidence worldwide but have unknown aetiology and limited therapeutic options beyond surgery. The current WHO classification, based on mitotic count and presence or absence of necrosis...

Active learning strategies for the estimation of a feasible set defined from a vector output black-box simulator

Many industrial problems require the use of black-box numerical simulators, for which it is essential to determine the set of so-called feasible input parameters. A set of parameters is feasible if the output of the code on these parameters satisfies given constraints, for exampl...