Eastern Liaoning University

SOHLH2 downregulation marks CD163-positive M2-like immunoregulatory marrow remodeling in acute myeloid leukemia: a single-center retrospective cohort study

The immunosuppressive marrow niche is a driver of acute myeloid leukemia (AML) persistence, yet transcriptional signals linked to macrophage skewing remain poorly defined. SOHLH2, a tumor-suppressive transcription factor in solid cancers, has not been characterized in AML. We inv...

Mandibular ramus osteotomy for resection of a deep prestyloid parapharyngeal space mass with skull base extension: a case report and technical note

Abstract Background Deep prestyloid parapharyngeal space (PPS) lesions with skull base extension may be difficult to access through standard surgical corridors because the mandibular ramus can restrict line-of-sight and instrument working angles, particularly near the carotid art...