Eastern Cooperative Oncology Group

Real‐World HRR Testing Pathways and Patterns of Detected Alterations in Prostate Cancer From the Multinational ARON‐3 Study

ABSTRACT Background Homologous recombination repair (HRR) testing is increasingly relevant in prostate cancer because it identifies patients who may benefit from biomarker‐guided treatment strategies, including poly(ADP‐ribose) polymerase inhibitors (PARPi). However, real‐world i...

Do carers of people with a chronic illness desire and seek psychological support? A quantitative systematic review

OBJECTIVE: This review systematically quantified engagement with psychological services among carers of people with chronic physical illness by determining the (a) prevalence and correlates of interest in, intention to access and use of services; and (b) availability of carer-spe...

Enhancing the financial sustainability of agricultural marketing cooperative societies (AMCOS) in Tanzania: lessons from longitudinal financial data

Agricultural Marketing Cooperative Societies (AMCOS) play a crucial role in supporting livelihoods, ensuring food security, and driving economic development. This study examines the financial sustainability of AMCOS and investigates the relationship between variables on sustainab...

Trop-2 overexpression as a prognostic marker in early triple-negative breast cancer: results from the GEICAM_CIBOMA trial

Trophoblast cell-surface antigen 2 (Trop-2) is a key therapeutic target in metastatic triple-negative breast cancer (TNBC), yet its prognostic significance in early-stage disease remains poorly defined. We evaluated Trop-2 expression and its clinical impact within a sub-cohort of...

Stereotactic Prostate Cancer Ablative Re‐Irradiation: A Systematic Review and Meta‐Analysis (SPARE)

ABSTRACT Background Stereotactic ablative radiotherapy (SABR) is emerging as an alternative treatment for patients with locally recurrent prostate cancer after previous radiation. This approach allows for precise target coverage while limiting toxicity to surrounding organs. Howe...

Global Real‐World Outcomes of Olaparib in Metastatic Castration‐Resistant Prostate Cancer Patients With Homologous Recombination Repair Alterations

Evidence to guide the treatment for patients with metastatic castration-resistant prostate cancer (mCRPC) and Homologous Recombination Repair (HRR) gene alterations outside of clinical trials remains limited. This was an observational, cohort study, including mCRPC patients with...