East West Medical College Hospital

CD147 drives keloid formation by promoting fibroblast proliferation via the CENPF signaling pathway

Keloids are benign dermal tumors, and keloid fibroblasts (KFs) play a critical role in their formation through hyperproliferation. However, the mechanism underlying this excessive fibroblast growth in keloids remains elusive. Here, we demonstrate that CD147 is upregulated in KFs...