East and North Hertfordshire NHS Trust

Screening strategies for the early detection of non-cardia gastric cancer in low- to moderate-prevalence regions: Asia-Pacific gastroesophageal cancer congress consensus 2026

Abstract Background Gastric cancer (GC) remains a major global health burden, and early detection is essential for improving patient outcomes. Although GC screening has been widely implemented in East Asian countries with a high disease burden, the optimal screening strategy for...

Conversational Agent-Based CBT Intervention for Anxiety and Depression in Medical Students: A Pilot Randomized Feasibility Study

Background: Medical students experience substantially higher rates of anxiety and depressive symptoms than similarly aged members of the general population. Academic, financial, and social pressures, together with concerns about stigma, may discourage timely engagement with conve...

Addressing evidence gaps in haemodialysis care: a critical review of clinical trials, technological innovations, and implementation priorities

Kidney failure treated with maintenance haemodialysis (HD) carries high risks of premature mortality, hospitalisation and impaired quality of life, yet important evidence gaps persist across routine HD care. The Dialysis Research Innovation Network, part of the UK Kidney Research...

Oral beta-D-glucan challenge to assess gut permeability in subjects receiving haemodialysis

Abstract Background Beta-D-glucan (BDG) levels are elevated in people receiving haemodialysis (HD), perhaps reflecting translocation of dietary BDG and gut-derived microbial products, and are a putative cause of HD-associated inflammation. BDG has been advocated as a marker of in...

Incidence and risk factors for postoperative myocardial infarction following hip and knee arthroplasty

Aims: Hip and knee arthroplasty are among the most commonly performed surgical procedures worldwide but carry a risk of cardiovascular complications, including myocardial infarction (MI). Therefore, this study aimed to assess the long-term incidence of MI following hip and knee a...