Duke Institute for Health Innovation

The global cardiovascular-kidney-liver-metabolic burden from 1990 to 2023

Background The cardiovascular-kidney-liver-metabolic (CKLM) framework represents the multi-organ interplay of systemic metabolic disorders that drive the global burden of cardiovascular diseases (CVD). Methods This study is a descriptive epidemiological analysis of the Global Bur...

Using insertable cardiac monitors to test determinants of heart rate and activity in captive baboons

Insertable cardiac monitors (ICMs) provide fine-grained, continuous data on cardiac activity. These data have great potential to reveal individual physiology, energetics, and stress responses, with implications for animal health, cognition, welfare, and conservation. However, the...

“She cannot use these methods before she has at least one child”: a qualitative study on family planning attitudes, knowledge, and experiences among adolescent girls and young women living with HIV in Moshi, Tanzania

Abstract Background Each year, about half of pregnancies in adolescents (15–19 years of age) are unintended, and the rate of adolescent pregnancy in sub-Saharan Africa is twice the global rate. Adolescent pregnancies have similar social determinants as those of HIV acquisition, r...