Dr. Behçet Uz Çocuk Hastalıkları Hastanesi

Retrospective Evaluation of the Clinical Characteristics, Laboratory Findings, and Treatment Approaches in Pediatric and Adolescent Patients Diagnosed with Type 2 Diabetes Mellitus: A Single-Center Experience

Background: The prevalence of type 2 diabetes mellitus (T2DM) in children has been increasing in parallel with the rise in obesity. Due to its insidious onset and slow progression, complications often manifest later in adulthood. This study aims to evaluate the clinical and labor...

Real-world outcomes of children with first relapsed acute lymphoblastic leukemia treated according to the ALL-IC REL 2016 guideline in Türkiye

Relapsed acute lymphoblastic leukemia (ALL) remains a major challenge in pediatric oncology, particularly where access to modern immunotherapies is limited. This national multicenter study evaluated real-world outcomes of children with first relapsed ALL treated according to the...

Evaluation of the pSOFA Score in a Pediatric Intensive Care Unit and Its Discriminative Performance Compared with PRISM 4 and PIM 3

Objectives: We aimed to evaluate the performance of the age-adapted Pediatric Sequential Organ Failure Assessment (pSOFA) score, as a predictor of mortality in patients admitted to pediatric intensive care units (PICUs), and to compare it with the Pediatric Risk of Mortality 4 (P...

Risk Factors for Drug Allergies in Pediatric Palliative Care Patients

Background / aim: Children receiving pediatric palliative care constitute a medically fragile population. Despite this vulnerable clinical profile, data on drug allergy in pediatric palliative care remain scarce. This study aimed to determine the frequency, clinical characteristi...

Pediatric DOCK8 Deficiency Beyond Infections and Atopy: An Immunoactinopathy with Immune Dysregulation and Multisystem Involvement

Background/Objectives: Dedicator of cytokinesis 8 (DOCK8) deficiency is an autosomal recessive combined immunodeficiency and an actin cytoskeleton-related inborn error of immunity characterized by severe atopy, recurrent infections, and broad immune dysregulation. We aimed to des...

Trichotillomania in bipolar spectrum adolescents is associated with an affective dysregulation phenotype: a multidimensional and cluster-analytic study

Trichotillomania (TTM) is a body-focused repetitive behavior that may function as an affect regulation strategy. In bipolar-spectrum youth, persistent emotion regulation difficulties may be particularly relevant for early recognition and intervention. In a cross-sectional design,...

Prediction of pediatric lower urinary tract dysfunction using uroflowmetry data and machine learning with explainable AI techniques

<title>Abstract</title> Purpose To develop and evaluate a machine learning based approach for the interpretation of uroflowmetry in pediatric lower urinary tract dysfunction, aiming to reduce interobserver variability and improve diagnostic consistency while maintaining clinical...