Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine

Efficacy of dietary supplements for treating pediatric metabolic dysfunction-associated steatotic liver disease: a systematic review and network meta-analysis

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major chronic liver disease in children. The comparative effects and safety of dietary supplements in children with MASLD remain uncertain. This systematic review and network meta-analysis compared their effect...

Acupuncture and Moxibustion for Neck Pain: A Clinical Practice Guideline

ABSTRACT Background Neck pain (NP) is a leading cause of disability worldwide. Pharmacological treatments often provide limited benefits and may be associated with adverse effects, highlighting the need for effective non‐pharmacological options. Aim To develop evidence‐based reco...

Iron deficiency-related abortion and miscarriage burden among women of advanced maternal age

Advanced maternal age (AMA) is associated with reduced fertility and higher risks of adverse pregnancy outcomes. Iron deficiency, a leading cause of anemia, has been associated with pregnancy loss. However, the iron deficiency-related burden among AMA women remains poorly quantif...

Semi-recumbent position for the prevention of ventilator-associated pneumonia in adults requiring mechanical ventilation

RATIONALE: Ventilator-associated pneumonia (VAP) is associated with increased mortality, hospital stay, and healthcare costs in critically ill patients. Although guidelines recommend a semi-recumbent position for VAP prevention, the evidence remains uncertain due to limitations i...

Associations of cumulative uric acid-to-high-density lipoprotein cholesterol ratio and its trajectories with cognitive outcomes in middle-aged and older adults with hypertension

The uric acid-to-high-density lipoprotein cholesterol ratio (UHR) integrates uric acid and lipid-related metabolic information, but its longitudinal association with cognitive outcomes in adults with hypertension is unclear. We analyzed data from 1,049 participants aged 45 years...

Association Between Rest–Activity Rhythm and Cardiovascular Disease, Cardiovascular Mortality, and All‐Cause Mortality: A Systematic Review and Meta‐Analysis

BACKGROUND: Disruption in rest-activity rhythm (RAR) is an emerging risk factor for cardiovascular disease (CVD) and mortality, but the strength of evidence is unclear. Therefore, we conducted a systematic review and meta-analysis to assess associations between RAR characteristic...

Clinical validation of the MED-58 upper-arm automated oscillometric blood pressure monitor with fan-shaped and rigid cuffs for home and clinical use in adolescents and adults, according to International Organization for Standardization 81060-2:2018 (Amd.1:2020; Amd.2:2024): a single-center prospective study

This study validated the accuracy and safety of the MED-58 upper-arm automated oscillometric blood pressure monitor - intended for home and clinical use - with fan-shaped and rigid cuffs, per International Organization for Standardization (ISO) 81060-2:2018 (Amd.1:2020; Amd.2:202...

The Lactate–Lactylation Axis as a Metabolic–Epigenetic Framework for Therapeutic Adaptation in Esophageal Squamous Cell Carcinoma

Therapeutic failure in esophageal squamous cell carcinoma (ESCC) can arise as tumor cells and their microenvironment adapt to sustained treatment pressure. The lactate–lactylation axis may connect altered metabolism with adaptive treatment responses through changes in protein and...

Efficacy and Safety Assessment of Upadacitinib for SAPHO Syndrome: A Retrospective Study of 35 Patients

OBJECTIVE: This study aimed to evaluate the efficacy and safety of upadacitinib administered over a short-term period in patients with SAPHO syndrome. METHODS: In this 12-week retrospective observational study, eligible SAPHO syndrome patients diagnosed within the past year and t...

Assessing traditional Chinese medicine service quality from physicians’ perspectives: a nationwide survey in China

Service quality is important for strengthening traditional Chinese medicine (TCM) within contemporary healthcare systems, yet provider-based evidence remains limited, particularly for TCM-specific aspects of clinical practice. We conducted a cross-sectional online survey of physi...

Comparative effectiveness of dietary supplements in dilated cardiomyopathy: a systematic review and network meta-analysis

Abstract Background Dilated cardiomyopathy (DCM) is a major cause of heart failure and cardiovascular mortality, partly due to impaired myocardial energy metabolism. Dietary supplements may offer benefits through improved mitochondrial function and antioxidant effects, and random...

Maxing Loushi Decoction alleviates COPD by targeting the PD-1/PD-L1 pathway: restoring Th17/Treg balance and inhibiting ferroptosis

Chronic obstructive pulmonary disease (COPD) is a progressive respiratory disorder driven by immune dysregulation and ferroptosis, with limited therapies addressing its underlying pathogenesis. Maxing Loushi Decoction (MXLS), a modified traditional Chinese medicine (TCM) formula,...

Effects of acupuncture on brain function in patients with depression

Background: Depression poses a major global health burden. Many patients exhibit treatment resistance or experience intolerable side effects with standard therapies. Acupuncture shows promise as an adjunctive therapy for depression, but its neurobiological mechanisms remain incom...