Dongguk University

Application of Physiologically Based Pharmacokinetic Modeling to Optimize Assessment of Age‐Related Fluoxetine Accumulation in the Elderly

ABSTRACT This study quantified age‐related differences in fluoxetine pharmacokinetics and evaluated the influence of CYP2D6 phenotype using physiologically based pharmacokinetic (PBPK) modeling integrated with clinical therapeutic drug monitoring data. A PBPK model for fluoxetine...

Application of Fibronectin-Coated Microparticles for Isolation of Human iPSC-Derived MSCs

Abstract BACKGROUND : Bone marrow–derived MSCs (BMMSCs) are limited by availability, donor variability, and age-related decline, highlighting the need for alternative MSC sources. Induced pluripotent stem cells (iPSCs) offer a scalable solution. This study introduces a novel thre...

Factors Influencing Older People's Disaster Preparedness Capacity: A Systematic Review

ABSTRACT Introduction Although disaster preparedness is an important issue for older people as disasters can affect their health, daily functioning and access to support, factors influencing their disaster preparedness capacity have not been comprehensively reviewed. Accordingly,...

Metabolic reprogramming of whey into fatty acid-based nitric oxide donors for controlling of recalcitrant multi-species biofilms in meat systems

Whey fermentation by lactic acid bacteria is a sustainable strategy to upcycle dairy byproducts into functional biomaterials; however, the molecular mechanisms underlying its anti-biofilm potential remain elusive. This study demonstrated the inhibitory mechanism of whey fermented...

Comparative evaluation of multicellular tumor spheroid fabrication platforms for reliable drug screening

Abstract Multicellular tumor spheroids (MTS) are widely used three-dimensional tumor models in various biomedical fields. Despite the increasing use of MTS, systematic comparisons providing practical information for selecting fabrication platforms according to experimental object...

A Dispersant‐Driven Carbon‐Binder Domains Homogeneity in High‐Energy‐Density Electrodes for Lithium‐Ion Batteries

Achieving high energy density in lithium-ion batteries (LIBs) requires electrodes with a high fraction of active materials. An extreme reduction of inactive components such as conductive additives and binders can limit electron transport and undermine electrode integrity, thereby...

Labor of the Bhikkhuni Sangha: Communal Work as Female Buddhist Practice

This study explores the role of labor as Buddhist practice within the Korean bhikkhuni sangha, with particular attention to ulryeok (communal labor). Bhikkhuni is not a term for a general female Buddhist practitioner, but a technical Buddhist term referring to a woman who has for...

Harnessing Diversity: Majority‐Group Acculturation Predicts Creativity and Flourishing Over Time

ABSTRACT Creativity and flourishing are core aims of higher education (HE) institutions and government initiatives globally. Large‐scale projects have linked creativity and flourishing with cultural diversity, yet their associations with majority‐group acculturation (i.e., how me...

Analysing Korean children's speech data for early childhood educational services: age-specific insights from text and audio analysis

Abstract As speech-based artificial intelligence (AI) becomes integrated into educational contexts, attention is growing towards its role in supporting child-centred learning environments. This study offers insights for developing child-friendly conversational AI systems by analy...

Coexisting Volatile and Nonvolatile Switching in 3D ALD‐IGZO Vertical RRAM for Fully Hardware‐Based Wide Reservoir Computing

ABSTRACT Although indium‐gallium‐zinc oxide (IGZO) has been widely used in thin‐film transistors (TFTs), its application as an active switching medium in resistive random‐access memory (RRAM) has remained relatively less explored, particularly for vertical RRAM (VRRAM) architectu...

Optoelectronic Resistive Switching Memory Enabled by a Zero‐dimensional Manganese(II) Hybrid Complex

ABSTRACT Lead‐free organic–inorganic hybrid metal halide compounds are emerging as promising alternatives to conventional lead‐based materials for optoelectronic applications. However, their implementation in non‐volatile memory devices remains largely unexplored. Herein, we repo...

Piezo1 Mechanotransduction in Skeletal Muscle: Convergence with Noncoding RNA Regulation in Myogenesis, Regeneration, and Sarcopenia

Skeletal muscle is a continuously load-bearing tissue whose growth, repair, and age-related decline are governed by mechanical signals; failure of this mechano-regulation underlies disuse atrophy and sarcopenia. Piezo1, a mechanically activated cation channel, has emerged as a tr...

Optimization of Poly-γ-Glutamic Acid Production by Moderate Electric Field-Assisted Fermentation in a Haematococcus pluvialis-Based Medium

Moderate electric field (MEF) fermentation was investigated as a nonthermal stress strategy to enhance the formation of extracellular polymeric substances (EPS; mucilage) by Bacillus subtilis HA in a Haematococcus-based medium. Response surface methodology (RSM), combined with a...

Synergistic Integration of SrFeO 3 Nanoparticles With Exfoliated MXene (Ti 3 C 2 T x /V 2 CT x ) Nanosheets for High Performance Supercapacitors

ABSTRACT The performance of supercapacitors is often limited by conventional electrode materials, which typically necessitate a compromise between energy density, power density, and cycling stability. While two‐dimensional MXenes offer high conductivity and surface area, their pr...

Interspecific variation in bamboo decay capacity of bambusicolous Apiospora species

Abstract Bambusicolous fungi play crucial roles in bamboo growth, health, disease, and lignocellulose decomposition. Among them, Apiospora species occupy diverse ecological niches as endophytes, pathogens, and saprotrophs. Fungal decay ability is an important functional trait for...

Morphological and Metabolic Changes During Callus-Based Shoot Regeneration in Chamaecyparis obtusa

Chamaecyparis obtusa is a valuable conifer species, prized for its high-quality timber and bioactive essential oils. However, commercial micropropagation is challenging due to its resistance to vegetative propagation. This study aimed to develop an efficient in vitro plant regene...

Recent Advances in Cryogel Applications for Musculoskeleatal Regeneration

Hydrogels have been widely used in tissue engineering due to their high-water content and biocompatibility, yet their densely cross-linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and cro...

Multi-Layered Electrospun Scaffold Design Strategies Targeting Osteosarcopenia

Osteosarcopenia, the concurrent deterioration of bone density and skeletal muscle mass and function, represents a growing clinical challenge in ageing populations worldwide. Conventional single-tissue therapeutic approaches fail to address the intricate biochemical and mechanical...