Dong-A University

Comparative metabolomic characterization of secondary metabolites in Gnaphalium affine D. Don considering the influence of growth stages and cultivation systems

Gnaphalium affine has long been consumed as a food and medicinal plant due to its nutritional and bioactive properties. This study comprehensively examined variation in metabolites and antioxidant activities across growth stages and between two cultivation environments of G. affi...

Association of Estimated Arterial Stiffness with Collateral Status and Functional Outcome after Endovascular Thrombectomy: A Secondary Analysis of the OPTIMAL-BP Trial

PURPOSE: Estimated pulse wave velocity (ePWV) is a surrogate of arterial stiffness that may influence stroke outcomes and potentially affect collateral circulation. We examined the association of ePWV with collateral status and 3-month functional outcome after successful endovasc...

Phase IIa Trial of Locoregional High-Dose Autologous Natural Killer Cell Therapy Combined with Hepatic Arterial Infusion Chemotherapy for Locally Advanced Hepatocellular Carcinoma

PurposeHepatocellular carcinoma (HCC) refractory to locoregional therapies remains a major clinical challenge.This study evaluated the efficacy and safety of locoregional high-dose autologous natural killer (NK) cell therapy combined with hepatic arterial infusion chemotherapy (H...

The role of deontological morality in shaping demand within the sharing economy

This study examines how deontological and consequentialist appeals in Airbnb host self-descriptions relate to trust-related attention and marketplace performance. Study 1 combines a five-city listing panel with third-party New York property-month records; Study 2 analyzes a behav...

The Impact of Adverse Childhood Experiences on Non-Suicidal Self-Injury Among Korean Adolescents: Moderating Effects of Social Support and Risk Profiling of Vulnerable Subgroups

Purpose: This study examined the prevalence of non-suicidal self-injury(NSSI) among Korean adolescents and investigated the independent and interactive associations of adverse childhood experiences(ACEs) and social support with NSSI. Methods: Data from a descriptive cross-section...

Spatializing Ageism in Commercial Spaces: Discursive Justifications and Lived Experiences of Age-Based Exclusion

Abstract This study examines how age-based exclusion is materially organized, discursively justified, and experienced within everyday commercial environments. Drawing on marketing systems theory and critical spatial theory, it conceptualizes commercial space as moral infrastructu...

Genomic Stress and DNA Repair During Macrophage Differentiation and Inflammatory Activation

Macrophages must preserve genome stability while performing immune and tissue-supporting functions that can themselves induce DNA damage or interfere with genome maintenance. Inflammatory metabolism produces reactive oxygen and nitrogen species, extensive transcription imposes to...

Uncertainty-aware active-learning design of high-strength, corrosion-resistant as-extruded Mg–Al–Zn–Mn–Ca–Y alloys using Bayesian neural networks

The present study proposes an uncertainty-aware design framework for as-extruded Mg–Al–Zn–Mn–Ca–Y alloys by integrating Bayesian neural network (BNN)-based property prediction, uncertainty-driven active learning (AL), and experimental validation. In the present AL cycle, tensile-...

Plasmonic Enhancement Using Yttrium Lithium Fluoride Hybrid Layers in a PCF-Based SPR Sensor for Biomolecule Detection

A high-performance plasmonic surface plasmon resonance (SPR) sensor with a tunable detection range is suggested in this paper. It uses gold (Au) in conjunction with yttrium lithium fluoride (YLiF4) as the adhesive layers, ensuring better sensing performance. We examined the impac...

Discordant Antitumor Efficacy with Compromised Survival in High-Risk Unresectable Hepatocellular Carcinoma

Background/Objectives: Real-world data in high-risk patients remain limited; this study evaluated survival, safety, and prognostic factors in this patient group. Methods: This multicenter study retrospectively reviewed 783 patients who received Ate/Bev from 2022–2024 across South...

Age- and sex-adjusted genomic differences between Korean and Beat AML cohorts

Genomic profiling plays a central role in risk stratification and therapeutic decision-making in acute myeloid leukemia (AML), yet the clinical implications of population-specific genomic architectures remain incompletely defined. We conducted a prospective, multicenter study of...

Lymph node development in human fetuses with special reference to the initial lymphocyte aggregation and intranodal sinuses

A mouse lymph node develops inside of five lymph sacs in the trunk. However, there are uninvestigated, numerous peripheral nodes. We chose histological sections from 38 human fetuses at approximately 8-31 weeks of gestational age (36 to 260 mm of crown-rump length). Three sites o...

Bridging primary care with artificial intelligence: toward a global 1.5-Tier Healthcare System

Artificial intelligence is increasingly applied in primary care, yet systematic frameworks linking individual applications to health-system improvement remain lacking. This perspective proposes a “1.5-Tier Healthcare System,” in which AI forms an intermediary layer between primar...

Korean Clinical Practice Guidelines for Rehabilitation in Critically Ill Patients and Post-Intensive Care Syndrome

Background: Survivors of critical illness commonly experience persistent physical, cognitive, and psychological impairments, collectively known as post–intensive care syndrome. Although intensive care unit (ICU) rehabilitation is now recognized as an important part of recovery af...

Effects of public hospital clerkship in rural and underserved areas in South Korea on medical students’ perceptions and career intentions: a pre–post study

PURPOSE: This study examined the short-term effects of a 2-week clinical clerkship program in rural and underserved public hospitals on medical students' perceptions of public healthcare and their intentions to work in non-metropolitan public hospital settings. METHODS: The Publi...

Balancing Injection and Short‐Channel Effects in Organic Permeable Base Transistors via Thickness Scaling

ABSTRACT Organic permeable base transistors (OPBTs) have attracted attention as vertical organic transistors that achieve high current density at a low operating voltage. While reducing organic semiconductor thicknesses is a common approach to improve performance in OPBTs, its su...

Beyond Dissolved Oxygen: Integrated Assessment of Multistage Vortex Aeration Effects on Urban Reservoir Water Quality

Aeration is widely used to increase the oxygen concentration in urban reservoirs, but its broader effect on nutrients, organic matter, and integrated water quality status remains uncertain. This study evaluated the response of the Jangrim reservoir, Busan, South Korea, to a multi...

Understanding the volatility of firm performance associated with corporate misconduct in the restaurant industry

Restaurant operators are often struggling to establish a robust governance and internal control system that protects against potential corporate wrongdoing. Whether purposely or unintentionally, restaurant firms’ engagement in corporate misconduct can increase the volatility of t...

Cancer nanovaccine plus doxorubicin and immune checkpoint blockade overcomes chemoresistance and delays postsurgical recurrence

Chemotherapy for solid tumors has serious limitations due to acquired chemoresistance and frequent postsurgical recurrence. In this study, we developed a chemo-immunotherapy regimen combining a chemotherapeutic agent, a dendritic cell (DC)-activating cancer nanovaccine, and immun...

Reinforcement learning-based decision support for admission-time inpatient bed allocation

Hospital bed allocation affects patient waiting, bed turnover, discharge flow, and queue accumulation. First-come, first-served (FCFS) is transparent but does not account for congestion, queue composition, expected length of stay (LOS), or downstream turnover. This study develope...