Dokuz Eylül University

Is Schneiderian phenomenology an interface between bipolar disorder and schizophrenia? Neurocognitive and neuroimaging evidence from a cross-sectional comparative study

Bipolar disorder (BD) and schizophrenia (SZ) show clinical and neurobiological overlap, but the position of psychotic BD within this spectrum remains uncertain. We tested whether BD with Schneiderian first-rank symptoms (P-BD) more closely resembled SZ than BD without lifetime ps...

MRI-derived lumbosacral cerebrospinal fluid volume influences both the extent and persistence of spinal anesthesia: a prospective observational study

Considerable interindividual variability exists in the spread and duration of spinal anesthesia despite standardized anesthetic techniques. Lumbosacral cerebrospinal fluid (CSF) volume has been proposed as an important anatomical determinant of neuraxial block characteristics. Ho...

A compilation of global bio-optical in situ data for ocean-colour satellite applications – version four

Abstract. A global in situ dataset for validation of satellite products from the ESA Ocean Colour Climate Change Initiative (OC-CCI) is presented. This version of the compilation, with data starting in 1996, extends to 2025, which is important for the validation of recent algorit...

Epigenetic reprogramming of lineage switching in cancer

Lineage plasticity develops as tumor cells overcome terminal differentiation barriers, adapt to environmental stressors, and acquire metastatic, therapy-resistant phenotypes. These phenotypic transitions are driven by nonmutational epigenetic mechanisms, including dynamic shifts...

Quality of Life Outcomes in Patients with Pulmonary Hypertension Receiving Prostacyclin Therapy: Impact of Anxiety, Depression, Sociodemographic Characteristics, and Treatment-Related Factors

OBJECTIVE: Despite advances in prostacyclin therapy, pulmonary hypertension (PH) continues to impair patients' quality of life (QoL). This study aimed to identify the clinical and psychological factors associated with QoL in patients receiving prostacyclin therapy. METHOD: This c...

Feeding and Husbandry Practices in Pet Ferrets ( Mustela putorius furo ): A Cross‐Sectional International Study

ABSTRACT Background The domestic ferret ( Mustela putorius furo ) is an increasingly popular non‐traditional companion animal; however, limited information is available on how caregivers manage feeding and husbandry practices. Objectives This study aimed to investigate feeding an...

Investigation of The Effects of Pre- and Postoperative Nutritional Status on Complication Development, Intensive Care Unit and Hospital Stay in Elective Cardiac Surgery Patients: A Cross-Sectional Study

Objective: The study aimed to examine the effects of nutritional status on complications, the intensive care unit, and hospital stay.Methods: This descriptive, prospective, and correlational study was conducted with 180 patients who underwent elective open-heart surgery. Data wer...

Protective Effect of Ozone on Liver Ischemia–Reperfusion (I/R) Injury in Streptozotocin-Induced Diabetic Rats

The aim of this study was to investigate the effects of ozone therapy on the liver, one of the organs most affected by ischemia–reperfusion damage in people with diabetes. Thirty male Wistar albino rats were used in this study. The rats were randomly divided into four groups: the...

How reliable is percutaneous transforaminal endoscopic discectomy during the learning curve? A comparison of outcomes with microsurgical discectomy experiences

We aimed to share our early experience with percutaneous transforaminal endoscopic discectomy (PTED) during the initial phase of the learning curve and to compare its clinical and perioperative outcomes with microsurgical discectomy (MD) in selected patients with symptomatic lumb...

Development and Internal Evaluation of an Integrated Patient–Embryo–Endometrial Scoring System for Predicting Biochemical Pregnancy in IVF: A Proof-of-Concept Pilot Study

Background/Objectives: Implantation in in vitro fertilization (IVF) depends jointly on patient prognosis, embryo quality and endometrial receptivity, yet these are usually assessed in isolation. We developed and internally evaluated, as a proof of concept, an index combining all...

Teacher-Mediated Digital Game-Based Learning and Children’s Emotional Intelligence in Inclusive Classrooms: A Systematic Review and Critical Narrative Synthesis

Digital game-based learning is increasingly used to support children’s engagement, interaction, and social–emotional development. However, its contribution to emotional intelligence, particularly in inclusive classroom contexts, remains theoretically underdeveloped and methodolog...

Awareness and educational needs regarding ultrasonography in dental education and practice among undergraduate and postgraduate dental students

This study aims to assess the level of knowledge, clinical awareness, and educational needs regarding ultrasonography (USG) among undergraduate and postgraduate dentistry students. This cross-sectional questionnaire-based study included 431 participants, comprising 231 postgradua...

Relationship Between EGFR Mutation Status and Clinicopathological Parameters in Non-Small Cell Lung Carcinomas and Correlation of PD-L1 Expression

Background and Objectives: In this study, we investigate clinical and pathological parameters that may be associated with EGFR mutations. We aimed to contribute to the literature by understanding other potential clinical and pathological factors that could be useful in predicting...

Experimental research: biomechanical evaluation of iliosacral screw fixation effects on sacral and iliac screw strain in lumbosacral and lumbopelvic constructs

Background: The biomechanical impact of iliosacral screw fixation (ISF) on lumbosacral fixation (LSF) and lumbopelvic fixation (LPF) constructs remains unclear. This study evaluates the effects of ISF on screw strain distribution and construct stability in these fixation models....

From anatomy to surgical safety: scenario-based learning for internal carotid artery patterns in undergraduate education

Abstract Background This study aimed to evaluate the educational value of scenario-based anatomy training using patient-specific three-dimensional models of internal carotid artery (ICA) anatomical patterns. Methods A total of 120 first-year medical students were assigned to eith...

Blood Pressure and Angina-Related Health Status During Benidipine Therapy: A Multicenter Real-World Cohort Study

Background: Benidipine is a long-acting calcium channel blocker used for the treatment of hypertension and chronic coronary syndrome. Although it effectively lowers blood pressure (BP), the relationship between BP reduction and improvement in angina-related health status during b...