Diyarbakır Gazi Yaşargil Eğitim ve Araştırma Hastanesi

Immunohistochemical investigation of suprabasin, isthmin-1, and podocalyxin immunoreactivity in basal cell carcinoma and trichoblastoma/trichoepithelioma

Objective Basal cell carcinoma (BCC) and trichoblastoma/trichoepithelioma (TB/TE) are skin tumors that may exhibit similar histopathological features. This study aimed to examine the immunoreactivity of suprabasin (SBSN), isthmin-1 (ISM-1), and podocalyxin (PODXL) BCC and TB/TE,...

Fibrinogen-to-Albumin, Platelet-to-Albumin, and Creatinine-to-Albumin Ratios in the Assessment of Preeclampsia Severity: A Retrospective Case–Control Study

Background: Preeclampsia (PE) is a multisystem pregnancy disorder associated with endothelial dysfunction, inflammation, and coagulation abnormalities. This study evaluated the fibrinogen-to-albumin ratio (FAR), platelet-to-albumin ratio (PAR), and creatinine-to-albumin ratio (Cr...

Language barriers, instruction comprehension, and spirometry failure in a multilingual outpatient population: a cross-sectional study

Spirometry quality depends on patients’ ability to understand and execute standardized instructions; however, the effects of language discordance and instruction comprehension difficulties on test performance remain insufficiently studied. This study examined whether native langu...

Ability of the HALP Score to Predict Cardiac Implantable Electronic Device‐Related Complications

BACKGROUND: The hemoglobin, albumin, lymphocyte, and platelet score (HALP) is a recently defined score that indicates patients' inflammation and nutritional status. This score is associated with poor outcomes in cardiovascular diseases. We aimed to examine the relationship betwee...

From Metabolism to Molecular Phenotype: Carbonic Anhydrase IX–Targeted [ 68 Ga]Ga-DPI-4452 PET/CT in Renal Cell Carcinoma: A Prospective Multicenter Comparison with [ 18 F]FDG PET/CT

The objective of this study was to prospectively compare the diagnostic performance, lesion detection capability, and clinical staging impact of [68Ga]Ga-DPI-4452 PET/CT with that of [18F]FDG PET/CT in renal cell carcinoma (RCC) using a multicenter design. Methods: Sixty-eight pa...

Longitudinal Anti-HBs Monitoring and Seroprotection Patterns in Rituximab-Treated Patients with Pemphigus Vulgaris: A Retrospective Cohort Study

Rituximab induces prolonged B-cell depletion and may alter protective antibody levels, but longitudinal antibody to hepatitis B surface antigen (anti-HBs) patterns in pemphigus vulgaris remain poorly characterized. This study evaluated anti-HBs levels and seroprotection after rit...

Age-associated medialization of the cervical internal carotid artery: CT morphometric findings and an exploratory combined mucosa–midline grading framework

Purpose Cervical internal carotid artery (ICA) medialization may narrow anatomical safety margins during transoral and pharyngeal procedures. We quantified age-associated ICA morphometric changes on computed tomography (CT), assessed age-based discrimination for study-defined cri...

Analysis of the value of lactate dehydrogenase to albumin ratio as a predictor of early mortality in patients with sigmoid volvulus undergoing emergency surgery

Aim: Sigmoid volvulus represents an important cause of mechanical large-bowel obstruction and may rapidly progress to life-threatening complications, particularly in elderly or frail patients. This study evaluated whether the preoperative lactate dehydrogenase-to-albumin ratio (L...

Video Yardımlı Torakoskopik Cerrahi (VATS) Uygulanan Hastalarda Postoperatif Analjezi Yönetiminde Paravertebral Blok ve İnterkostal Bloğun Karşılaştırılması: Retrospektif Çalışma

Amaç: Bu çalışmanın primer amacı, video yardımlı torakoskopik cerrahi (VATS) uygulanan hastalarda paravertebral blok (PVB) ve interkostal blok (İKB) yöntemlerinin postoperatif ağrı kontrolündeki etkinliğini statik ve dinamik görsel analog skala (VAS) skorları üzerinden karşılaştı...

Çocukluk Çağı Akut Lösemilerinde Febril Nötropeni: Klinik ve Mikrobiyolojik Değerlendirme

Amaç: Bu çalışmada, akut lösemi tanılı pediatrik hastalarda kemoterapi ile ilişkili febril nötropeni (FN) ataklarında bakteriyemi sıklığının ve etken mikroorganizmaların belirlenmesi; bakteriyemi ve tedavi sonuçlarıyla ilişkili klinik özelliklerin değerlendirilmesi amaçlandı.Yönt...

Regular AREDS2 Supplement Use in Age-Related Macular Degeneration: Factors Associated with Supplementation, Medication Adherence, and Patient-Reported Barriers

Background/Objectives: Age-related macular degeneration (AMD) is a leading cause of irreversible visual impairment, and AREDS2-based nutritional supplementation is recommended for clinically eligible patients to reduce the risk of disease progression. However, successful implemen...

Dural Puncture Epidural, Standard Epidural, and No Epidural: Comparative Effects on Labor Progression and Neonatal Outcomes

Objective: To compare non-epidural labor, standard epidural analgesia, and dural puncture epidural analgesia with respect to labor progression, obstetric outcomes, analgesia-related outcomes, and neonatal results. Methods: This single-center retrospective observational cohort stu...

A simulation-based optical safety framework for dermatologic laser wavelength selection across Fitzpatrick skin phototypes

Abstract Laser wavelength selection in dermatology remains challenging across diverse skin phototypes, where inappropriate choice may increase the risk of epidermal injury. This study develops a simulation-based optical safety framework to support wavelength selection by quantify...