Deyang Stomatological Hospital

Clinical value of artificial intelligence ultrasound-assisted diagnostic system in the differential diagnosis of benign and malignant thyroid nodules

Accurately distinguishing the benign thyroid nodules (BTNs) and malignant thyroid nodules (MTNs) is crucial for treatment planning and prognosis. This study aims to explore the clinical value of artificial intelligence ultrasound-assisted diagnostic system (AI-UADS) in diagnosing...

Identification of Risk Factors for Postoperative Delirium and Targeted Preventive Strategies in Elderly Patients in the Emergency Surgical ICU

AIM: Elderly patients admitted to the intensive care unit (ICU) after emergency surgery represent a uniquely high-risk population for postoperative delirium (POD). However, the key risk factors specific to this group have not been comprehensively integrated, and a corresponding c...

Mefatinib versus gefitinib as a first-line treatment for EGFR-mutated non-small cell lung cancer: a randomized, double-blind, multicenter phase III study

Mefatinib, a novel second-generation epidermal growth factor (EGFR) tyrosine kinase inhibitor that has shown promising antitumor activity in targeting non-small cell lung cancer (NSCLC) with common and uncommon EGFR- activating mutations. In this phase III, randomized, double-bli...

Impact of IL-6 receptor inhibitors on cerebrospinal fluid metabolites in type 2 diabetes patients

This study aimed to investigate whether interleukin-6 (IL-6) receptor inhibitors affect cerebrospinal fluid (CSF) metabolites in type 2 diabetes (T2D) patients. The initial phase employed drug-targeted Mendelian randomization to investigate the association between IL-6 receptor i...

lnc-HOTAIR inhibits MTHFR expression to regulate endothelial cell proliferation and apoptosis in aSAH-induced cerebral vasospasm

Abstract Background: Cerebral vasospasm (CVS) following aneurysmal subarachnoid hemorrhage (aSAH) is a major cause of disability and mortality, yet its pathogenesis remains incompletely understood. long non-coding RNA HOX Transcript Antisense RNA (lnc-HOTAIR) is involved in the r...