Deutsches Konsortium für Translationale Krebsforschung

Molecular characterization of mismatch repair deficient tumors in young Jordanian patients

<title>Abstract</title> In Jordan, approximately 19% of colorectal carcinomas (CRCs) in patients younger than 45 years show mismatch repair deficiency (MMRD) by immunohistochemistry (IHC). MMRD in pediatric high-grade gliomas (HGG) and CRC in Jordan appears substantially more fre...

Accelerating Translation of NK Cell Therapies to the Clinic: A European Perspective

Adoptive immunotherapies have emerged as a promising strategy in the treatment of hematological malignancies. To date, seven chimeric antigen receptor (CAR)-T cell products have obtained market authorization in Europe for B-cell malignancies, where they have revolutionized treatm...