Deutsches Herzzentrum München

The zlog value: a decade of standardizing laboratory results

Abstract Background The zlog transformation was developed in 2016 as a method-independent and unit-independent standardization of laboratory results for the German Electronic Health Record (ePA). Based on the assumption of a log-normal distribution and the known lower and upper r...

Early evaluation of the WCT EVI MAP project: implementation, challenges, and emerging impact on evidence-based tumour classification

<ns5:p>Background The WHO Classification of Tumours (WCT) underpins cancer diagnosis globally, but the evidence-base used to inform tumour classification has never been systematically appraised. The WCT EVI MAP project was designed to address this need by developing a structured,...

Tirzepatide and the risk of atherosclerotic cardiovascular events: population based cohort study

Abstract Objective To estimate the magnitude of reduction in major adverse cardiovascular events (MACE) that would be observed in clinical practice from adding tirzepatide to standard of care treatment. Design Population based cohort study, using a design, data, and analytical ap...