Department of Embryology

Reconstitution of lamin assembly on nuclear pore complex-containing membranes

Intermediate filaments called lamins line the metazoan nuclear envelope and organize the nucleus and genome. Unlike actin and microtubules, purified intermediate filament proteins assemble into non-physiological structures, making it difficult to connect lamin functions to their...

Enhancing Oligodendrogenesis Rescues Chronic Stress‐Induced Behavioral Disorders Involving Neuronal and Synaptic Reorganization

ABSTRACT Chronic stress induces psychiatric disorders, including depression and anxiety, yet effective therapies remain limited. Myelin in adult brains undergoes dynamic remodeling through oligodendrocyte precursor cells (OPCs) differentiation into oligodendrocytes (OLs) and the...

Protective Effect of Ozone on Liver Ischemia–Reperfusion (I/R) Injury in Streptozotocin-Induced Diabetic Rats

The aim of this study was to investigate the effects of ozone therapy on the liver, one of the organs most affected by ischemia–reperfusion damage in people with diabetes. Thirty male Wistar albino rats were used in this study. The rats were randomly divided into four groups: the...

Protective or Therapeutic Effect of Exosomes Isolated From Mesenchymal Stem Cells on Cisplatin‐Induced Ovarian Damage

ABSTRACT Cisplatin (Cis), an index drug with the greatest gonadotoxic potential, affects both primordial follicles and developing follicles (pre‐antral) in vivo. Mesenchymal stem cell‐derived exosomes accelerate cell proliferation and wound healing. Exosomes have been shown to in...

A 14-day repeated dose oral toxicity assessment of the aqueous-ethanolic extract of Schouwia purpurea in female Wistar albino mice

Schouwia purpurea (Family: Brassicaceae) S. purpurea is a wild medicinal plant traditionally used for treating gastrointestinal, inflammatory, and infectious disorders in arid regions of North Africa. Despite its ethnomedicinal importance, little is known about its systemic safet...