Departament de Salut

Anticholinergic burden in older adults with hyperpolypharmacy: a comparison of the drug burden index, anticholinergic cognitive burden, and duran scales in primary care

Abstract To evaluate anticholinergic burden in older adults (≥ 65 years) with hyperpolypharmacy (≥ 10 medications) in primary care using the Drug Burden Index (DBI), and to compare the results with those obtained using the Anticholinergic Cognitive Burden (ACB) scale and Duran’s...

Refining risk stratification after indeterminate urinary cytology: Evidence from Bladder EpiCheck

BACKGROUND: This study aimed to evaluate Bladder EpiCheck (BE) performance in detecting urothelial carcinoma (UC) and HG (high-grade) events in patients with indeterminate cytology and negative cystoscopy. METHODS: This prospective study included 63 patients who presented with in...

Treating a Disorder Caused by an Overactive Enzyme: BCKD‐Kinase Deficiency

ABSTRACT Branched‐chain ketoacid dehydrogenase kinase (BCKDK) deficiency is a rare autosomal recessive disorder. Loss of this kinase leaves the branched‐chain α‐ketoacid dehydrogenase complex constitutively active, leading to depletion of branched‐chain amino acids (BCAAs) rather...

Methodology for assessing sleep quality and its parameters in the context of neurophysiological and behavioral aspects

Sleep is a fundamental physiological process essential for maintaining cognitive function, emotional stability, and overall health. This paper reviews various parameters influencing sleep quality, including total sleep duration, sleep latency, continuity and stability (restfulnes...