Delta University for Science and Technology

Hibiscus sabdariffa protects against fibromyalgia by modulating the neuroinflammation–oxidative stress–microRNA axis

Fibromyalgia (FM) is a chronic syndrome characterized by widespread pain, fatigue, cognitive dysfunction and neuropsychiatric disturbances, associated with dysregulated oxidative stress and neuroinflammation. Emerging evidence suggests that microRNAs guiding these pathways, inclu...

Beyond Nrf2 Activation: A Proposed Sulforaphane-Selenium Strategy for Oxidative Stress in COPD

Chronic Obstructive Pulmonary Disease (COPD) is characterized by marked and persistent oxidative stress, which contributes to chronic inflammation, cellular senescence, and progressive lung dysfunction. However, conventional therapies, including corticosteroids and traditional th...

Metaheuristic-Based PI Controller Tuning Using a Multi-Error ITAE Objective Function for FOC-Controlled PMSM Drives in Electric Vehicle Applications

Permanent Magnet Synchronous Motors (PMSMs) are widely employed in electric vehicle (EV) propulsion systems because of their high efficiency, high power density, and superior dynamic performance. The performance of field-oriented control (FOC)-based PMSM drives strongly depends o...

CD38 Inhibition Enhances FXR Signaling in Male Rats With Diabetic Steatohepatitis Through SIRT1‐Dependent Suppression of NLRP3

ABSTRACT Diabetic steatohepatitis, now clinically framed within metabolic dysfunction‐associated steatohepatitis (MASH), features progressive disruption of hepatic microarchitecture alongside sterile inflammatory microdomains. Farnesoid X receptor (FXR) activity is restrained by...

Fasudil Protects Against Diclofenac-Induced Hepatorenal and Gastric Injury via Modulation of ROCK/TLR4/SIRT1 Signaling and Preservation of Tight Junctions

Background: Diclofenac is a widely consumed non-steroidal anti-inflammatory drug, yet its clinical utility is limited by severe hepatotoxicity, acute kidney injury, and gastric ulceration. While the RhoA/ROCK pathway is implicated in inflammation, its potential as a therapeutic t...

The Role of Accounting Information Quality in Attracting Foreign Investment

تهدف الدراسة إلى تحليل الغلاقة بين جودة المعلومات المحاسبية وقرارات المستثمرين الأجانب وإختبار ما إذا كانت البيانات والمعلومات المالية ذات الجودة العالية من حيث الموثوقية والشفافية تساهم في جذب الاستثمارات الخارجية. وتأتي أهمية البحث من اعتماد المستثمرين الأجانب على التقارير الما...