Delhi Pharmaceutical Science and Research University

Impact of vestibular-based intervention on movement and postural stability in children with spastic cerebral palsy: a single-blind randomized controlled trial

Background and objective Cerebral Palsy (CP) is not only associated with neuromuscular impairments, but also with sensory processing alterations, due to disrupted thalamocortical projections caused by white matter lesions. This study aimed to evaluate the effectiveness of Convent...

Heavy metal induced cellular proteostasis failure promotes neurodegeneration and therapeutic opportunities

Exposure to heavy metals is a significant environmental risk factor for neurodegenerative diseases. Persistent exposure to heavy metals including lead, mercury, cadmium, manganese, copper, and arsenic are all examples of non-biodegradable, bioaccumulative toxicants that can cross...

Leveraging exosomes and lipid nanoparticles based nanomedicine for cervical cancer therapeutics

Cervical cancer (CC) remains a significant global health burden, ranking as the fourth most common cancer among women worldwide. Persistent infection with high-risk human papillomavirus (HPV) is the primary etiological factor, although tumor progression is also influenced by gene...

Mapping the financial mindscape: a bibliometric and content analysis of financial literacy, mindfulness, and well-being

Abstract The complexities of financial decisions and their economic consequences have drawn global research interest; however, the integrated study of financial literacy, mindful finance, and financial well-being has been largely overlooked in prior reviews, limiting understandin...

Sustainable assessment of analytical techniques in COVID-19 pharmacotherapy: A greenness perspective

The rapid development of analytical methods during the COVID-19 pandemic has pointed to the importance of chromatographic and mass spectrometric systems for drug quantification. In this review, the ecological sustainability of HPLC, UHPLC, LC-MS and LC-MS/MS workflows is critical...

Capsaicin and diclofenac coloaded nanoemulsion gel optimized by quality by design approach of for the treatment of rheumatoid arthritis

Aims Rheumatoid arthritis (RA) is a chronic inflammatory disorder associated with progressive joint damage and pain. The present study aimed to develop and optimize a capsaicin – diclofenac-loaded nanoemulgel incorporating clove and olive oil for enhanced topical delivery and the...

In silico investigation of novel isatin derivatives as potential multi-target anticancer agents targeting VEGFR-2, EGFR, and caspase-6

The isatin scaffold has emerged as a promising platform for the development of anticancer agents, as evidenced by several clinically relevant isatin-based compounds. In this study, 85 novel isatin derivatives were designed based on literature reports and evaluated using drug-like...