Dartmouth Health

Hearts too small for body size after doxorubicin for childhood acute lymphoblastic leukemia: Grinch Syndrome

Cardiovascular disease is a major cause of morbidity and mortality in childhood cancer survivors. We assessed the very long-term cardiac structure and function of adult survivors of childhood leukemia treated with anthracycline-based therapy. One hundred fifteen patients with hig...

Large Language Models (LLMs) vs Manual Chart Review for Assessing Goal-Concordant Care: An Exploratory Study

BackgroundEvidence that advance care planning (ACP) improves goal-concordant care (GCC) remains limited. Challenges are lack of reproducible operational definition of GCC and labor-intensive nature of manual chart review.ObjectivesDevelop a structured approach to adjudicating GCC...