Danylo Halytsky Lviv National Medical University

A chaotropic agent-assisted, AQbD-guided RP-HPLC method for the simultaneous determination of rosuvastatin, atorvastatin, and ezetimibe: a rapid, robust, and green approach

The simultaneous determination of rosuvastatin, atorvastatin, and ezetimibe in pharmaceutical formulations is challenging due to their distinct physicochemical properties. This study details the development and validation of a rapid, robust, and stability-indicating reversed-phas...

Tick-borne encephalitis co-occurring with human herpesvirus 7 replication: a case report and literature review

We report a case of tick-borne encephalitis (TBE) in an immunocompetent 53-year-old female patient who was admitted to our hospital on the 16th day of illness in moderately severe condition with a body temperature up to 38.4 °C and clinical signs of meningoencephalitis. Following...

Synergism of triggers for loss of asthma control in children during wartime

Abstract Background Children with asthma living in areas affected by armed conflict are exposed to a unique combination of psychological stress, environmental hazards, healthcare disruption, and adverse social conditions that may contribute to poorer asthma control. Although thes...

(Z)-3′-(3-Chloro-4-fluorophenyl)-5-fluoro-5′-((6-methoxypyridin-3-yl)methylene)spiro[indoline-3,2′-thiazolidine]-2,4′-dione

A novel spiro[indoline-3,2′-thiazolidine]-2,4′-dione derivative incorporating 3-chloro-4-fluorophenyl and 6-methoxypyridin-3-yl fragments was synthesized and characterized. The synthetic route involved a two-step procedure, including the preparation of the spirocyclic scaffold vi...