Danish Pain Research Center

Assessment of blinding in pharmacotherapy and noninvasive neuromodulation randomized controlled trials for neuropathic pain in adults

In randomized controlled trials (RCTs), study participants and research personnel are often blinded to minimize biases related to knowing treatment allocation. To determine if blinding was effective, participants may be asked which treatment they believe they received (“treatment...

Global analysis of thermal and chemical denaturation using CheMelt : Thermodynamic dissection of highly thermostable de novo designed proteins

ABSTRACT De novo protein design often produces thermostable proteins that denature above 100 °C, which complicates the analysis of their stability. Thermostable proteins can be unfolded by combined chemical and thermal denaturation followed by global analysis of multiple melting...

Problem-driven design methods for organizing collaborative learning: learning circles and change laboratories

Purpose This study aims to examine how two Nordic co-design methods, namely, learning circles (LC) and change laboratory (CL), support collaborative learning and system-level redesign in educational settings. The authors identify learning and facilitation principles that guide th...