Institution
Dana-Farber/Boston Children's Cancer and Blood Disorders Center
Recent research
- Health & Medicine
O.L. is a named inventor on patents held by Boston Children's Hospital related to vaccine adjuvants and antigens as well as human in vitro systems that model the safety and immunogenicity of vaccines and immunotherapeutics. O.L.’s laboratory receives sponsored research support fr...
- BiologyOpen access
Facile, high‐throughput protein purification enabled by high‐efficiency protease elution
Abstract While advances in artificial intelligence have made protein design widely accessible, protein production and characterization remain a bottleneck. Protease‐cleavable affinity tags are commonly used to improve yield and purity of recombinant proteins, but tag removal adds...
- Health & Medicine
Access to Anticancer Drug Trials for Adolescents With Cancer in the United States
BACKGROUND: Adolescents with cancer are generally underrepresented in clinical trials. The extent to which cancer drug clinical trials have become more age inclusive over time is not clear. METHODS: We utilized ClinicalTrials.gov to identify cancer drug trials from 2005 to 2025 i...